trophoblastn.

Brit.

/ˈtrɒfəblɑːst/,

/ˈtrəʊfəblɑːst/,

/ˈtrɒfəblast/,

/ˈtrəʊfəblast/, U.S.

/ˈtroʊfəˌblæst/,

/ˈtrɑfəˌblæst/

Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: tropho- comb. form, -blast comb. form.

Etymology: < tropho- comb. form + -blast comb. form, after German Trophoblast (1886 or earlier in sense 1; A. A. W. Hubrecht 1888, in Anatomischer Anzeiger 3 511, in sense 2).With sense 1, compare slightly earlier tropholecithus n. at tropho- comb. form 1. With sense 2, compare French trophoblaste (1888 in a comment on Hubrecht's paper).

Embryology.

†1. Nutritive substance or tissue (perhaps yolk) within a developing ovum. Cf. tropholecithus n. at tropho- comb. form 1. Obsolete. rare.

ΘΚΠ

the world > life > biology > biological processes > procreation or reproduction > reproductive substances or cells > [noun] > ovum or ootid > yolk

yolkeOE

spring1600

vitellary1650

vitellus1728

food-yolk1850

vitellin1857

trophoblast1886

vitelline1891

ovovitellin1906

1886 Jrnl. Royal Microsc. Soc. 6 940 The nuclei which appear beneath the blastoderm in the trophoblast sink downwards and take on the characters of cells.

2. The layer of cells surrounding a blastocyst, which attaches to, invades, and proliferates in the uterine lining in the early stages of implantation, allowing the embryo to receive nutrients from the mother, and which contributes to the formation of the placenta.The trophoblast itself develops two layers; see cytotrophoblast n. and syncytiotrophoblast n. at syncytium n. Derivatives.In quot. 1907, used with reference to a former theory that cancerous tissue is of the same nature as trophoblast.

ΘΚΠ

the world > health and disease > ill health > a disease > growth or excrescence > [noun] > tumour > malignant tumours

cancer1527

carcinoma1583

crab1614

scirrhus1759

sarcoma1804

malignant melanoma1838

melanocarcinoma1857

adenosarcoma1871

adenocarcinoma1872

angiosarcoma1873

lymphosarcoma1874

mycosis fungoides1874

melanosarcoma1875

osteosarcoma1876

chondrosarcoma1883

psammosarcoma1886

trophoblast1889

liposarcoma1893

multiple myeloma1897

sarcoid1899

leiomyosarcoma1914

spongioblastoma1918

osteogenic sarcoma1923

sympathicoblastoma1927

reticulosarcoma1928

carcinoma in situ1932

malignancy1934

teratocarcinoma1946

sympathoblastoma1960

sympathogonioma1966

sympathicogonioma1974

the world > life > biology > biological processes > procreation or reproduction > embryo or fetus > embryo parts > [noun] > trophoblast

trophoblast1889

plasmoditrophoblast1905

trophectoderm1915

syncytiotrophoblast1926

1889 A. A. W. Hubrecht in Q. Jrnl. Microsc. Sci. 30 298 The first new name of which I want definitely to establish the significance (it was first used by me in the ‘Anat. Anzeiger’, vol. iii, p. 511) is the name trophoblast. I propose to confer this name to the epiblast of the blastocyst as far as it has a direct nutritive significance, as indicated by proliferating processes, by immediate contact with maternal tissue, maternal blood, or secreted material.

1907 Contemp. Rev. Sept. 411 A cancer is ‘irresponsible trophoblast’.

1951 G. R. de Beer Vertebr. Zool. (ed. 2) xiv. 195 The blastocyst travels down the oviduct and eventually finds itself in the cavity of the uterus where it ingests through its trophoblast the nutritive substances secreted by the uterine glands.

1980 Sci. Amer. Aug. 82/2 (caption) As the invasion proceeds the trophoblast differentiates into two layers, the outer syncytiotrophoblast, which leads the advance into the endometrium, and the cytotrophoblast.

2003 Independent 17 Jan. i. 9/2 By coating latex beads with the type of carbohydrates found in the uterus lining, the scientists demonstrated they stuck readily to the outer cells of an embryo, called the trophoblast, at the critical stage of development when it was normally ready for implantation.

Derivatives

ˌtrophoˈblastic adj. of or relating to trophoblast; derived from or of the nature of trophoblast.

ΚΠ

1889 A. A. W. Hubrecht in Q. Jrnl. Microsc. Sci. 30 301 Mesoblastic warts, ridges, and outgrowths being soon surrounded on three sides by the trophoblastic proliferation.

1913 J. W. Jenkinson Vertebr. Embryol. ix. 254 The syncytial and cellular layers lining the sinuses and covering the villi are then both trophoblastic in origin.

1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) II. lxix. 1639/2 Trophoblastic tumors such as the hydatidiform mole.

2011 S. Zamudio in H. H. Kay et al. Placenta vi. 45/1 Loss of the trophoblastic plugs leads to a steep rise in oxygenation at the end of the first trimester.

This entry has been updated (OED Third Edition, March 2014; most recently modified version published online March 2022).

单词	trophoblast
释义	trophoblastn. Brit. /ˈtrɒfəblɑːst/, /ˈtrəʊfəblɑːst/, /ˈtrɒfəblast/, /ˈtrəʊfəblast/, U.S. /ˈtroʊfəˌblæst/, /ˈtrɑfəˌblæst/ Origin: Formed within English, by compounding; modelled on a German lexical item. Etymons: tropho- comb. form, -blast comb. form. Etymology: < tropho- comb. form + -blast comb. form, after German Trophoblast (1886 or earlier in sense 1; A. A. W. Hubrecht 1888, in Anatomischer Anzeiger 3 511, in sense 2).With sense 1, compare slightly earlier tropholecithus n. at tropho- comb. form 1. With sense 2, compare French trophoblaste (1888 in a comment on Hubrecht's paper). Embryology. †1. Nutritive substance or tissue (perhaps yolk) within a developing ovum. Cf. tropholecithus n. at tropho- comb. form 1. Obsolete. rare. ΘΚΠ the world > life > biology > biological processes > procreation or reproduction > reproductive substances or cells > [noun] > ovum or ootid > yolk yolkeOE spring1600 vitellary1650 vitellus1728 food-yolk1850 vitellin1857 trophoblast1886 vitelline1891 ovovitellin1906 1886 Jrnl. Royal Microsc. Soc. 6 940 The nuclei which appear beneath the blastoderm in the trophoblast sink downwards and take on the characters of cells. 2. The layer of cells surrounding a blastocyst, which attaches to, invades, and proliferates in the uterine lining in the early stages of implantation, allowing the embryo to receive nutrients from the mother, and which contributes to the formation of the placenta.The trophoblast itself develops two layers; see cytotrophoblast n. and syncytiotrophoblast n. at syncytium n. Derivatives.In quot. 1907, used with reference to a former theory that cancerous tissue is of the same nature as trophoblast. ΘΚΠ the world > health and disease > ill health > a disease > growth or excrescence > [noun] > tumour > malignant tumours cancer1527 carcinoma1583 crab1614 scirrhus1759 sarcoma1804 malignant melanoma1838 melanocarcinoma1857 adenosarcoma1871 adenocarcinoma1872 angiosarcoma1873 lymphosarcoma1874 mycosis fungoides1874 melanosarcoma1875 osteosarcoma1876 chondrosarcoma1883 psammosarcoma1886 trophoblast1889 liposarcoma1893 multiple myeloma1897 sarcoid1899 leiomyosarcoma1914 spongioblastoma1918 osteogenic sarcoma1923 sympathicoblastoma1927 reticulosarcoma1928 carcinoma in situ1932 malignancy1934 teratocarcinoma1946 sympathoblastoma1960 sympathogonioma1966 sympathicogonioma1974 the world > life > biology > biological processes > procreation or reproduction > embryo or fetus > embryo parts > [noun] > trophoblast trophoblast1889 plasmoditrophoblast1905 trophectoderm1915 syncytiotrophoblast1926 1889 A. A. W. Hubrecht in Q. Jrnl. Microsc. Sci. 30 298 The first new name of which I want definitely to establish the significance (it was first used by me in the ‘Anat. Anzeiger’, vol. iii, p. 511) is the name trophoblast. I propose to confer this name to the epiblast of the blastocyst as far as it has a direct nutritive significance, as indicated by proliferating processes, by immediate contact with maternal tissue, maternal blood, or secreted material. 1907 Contemp. Rev. Sept. 411 A cancer is ‘irresponsible trophoblast’. 1951 G. R. de Beer Vertebr. Zool. (ed. 2) xiv. 195 The blastocyst travels down the oviduct and eventually finds itself in the cavity of the uterus where it ingests through its trophoblast the nutritive substances secreted by the uterine glands. 1980 Sci. Amer. Aug. 82/2 (caption) As the invasion proceeds the trophoblast differentiates into two layers, the outer syncytiotrophoblast, which leads the advance into the endometrium, and the cytotrophoblast. 2003 Independent 17 Jan. i. 9/2 By coating latex beads with the type of carbohydrates found in the uterus lining, the scientists demonstrated they stuck readily to the outer cells of an embryo, called the trophoblast, at the critical stage of development when it was normally ready for implantation. Derivatives ˌtrophoˈblastic adj. of or relating to trophoblast; derived from or of the nature of trophoblast. ΚΠ 1889 A. A. W. Hubrecht in Q. Jrnl. Microsc. Sci. 30 301 Mesoblastic warts, ridges, and outgrowths being soon surrounded on three sides by the trophoblastic proliferation. 1913 J. W. Jenkinson Vertebr. Embryol. ix. 254 The syncytial and cellular layers lining the sinuses and covering the villi are then both trophoblastic in origin. 1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) II. lxix. 1639/2 Trophoblastic tumors such as the hydatidiform mole. 2011 S. Zamudio in H. H. Kay et al. Placenta vi. 45/1 Loss of the trophoblastic plugs leads to a steep rise in oxygenation at the end of the first trimester. This entry has been updated (OED Third Edition, March 2014; most recently modified version published online March 2022). < n.1886
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