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单词 triamterene
释义

triamterenen.

/trʌɪˈamtəriːn/
Forms: Also triamterine.
Etymology: < triam- (in triamine n.) + -terene altered < pteridine n.
Pharmacology.
A yellow crystalline powder, C12H11N7, used as a mild diuretic, usually as an adjunct to other diuretic drugs in cases where increased excretion of potassium is undesirable; 6-phenylpteridine-2,4,7-triamine.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific
Haarlem oil1885
Salyrgan1924
mersalyl1936
acetazolamide1954
chlorothiazide1957
thiazide1959
triamterene1962
ethacrynic acid1963
frusemide1963
1962 Ann. Internal Med. 56 241/1 Observations in rats and dogs..demonstrated that triamterene (SK&F No. 8542)..possessed antimineralo-corticoid activity.
1964 Brit. Med. Jrnl. 13 June 1557/1 Triamterine is a pteridine compound (2,4,7-triamino-6-phenylpteridine) and is chemically unrelated to any of the previously available diuretics.
1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xi. 10/1 Triamterene increases the renal excretion of Na+ and Cl in approximately equal amounts and has no effect on HCO3 excretion.
1985 Brit. Med. Jrnl. 9 Nov. 1337/1 Folate may be antagonised by..triamterene.
1987 M. J. Neal Med. Pharmacol. at Glance xiii. 33/2 Amiloride and triamterene decrease the luminal membrane Na+ permeability in the distal nephron.
This entry has not yet been fully updated (first published 1993; most recently modified version published online December 2020).
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n.1962
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