transdermaladj.

Brit.

/tranzˈdəːml/,

/trɑːnzˈdəːml/,

/transˈdəːml/,

/trɑːnsˈdəːml/, U.S.

/trænzˈdərm(ə)l/,

/træn(t)sˈdərm(ə)l/

Origin: Formed within English, by derivation. Etymons: trans- prefix, dermal adj.

Etymology: < trans- prefix + dermal adj.

Medicine.

1. Passing, occurring, or effected through or across the skin.

ΚΠ

1907 T. W. Jackson Trop. Med. ii. iv. 423 This hypothesis of transdermal miracidium-infection requires proof.

1916 T. W. Brophy Oral Surg. I. viii. 122 In wounds about the face, transdermal stitches should be passed only through the corium.

1969 Acta Otolaryngol. 67 69 (title) Hearing rehabilitation by means of transdermal electrotherapy.

1988 New Scientist 7 Apr. 26/3 Transdermal potential, a voltage between the outer layers of the skin and the tissues below, is the key to solving the problem.

2001 J. M. Ntambi & Y.-C. Kim in N. Moustaïd-Moussa & C. D. Berdanier Nutrient–Gene Interactions in Health & Dis. iii. 52 Increased transdermal water loss, and impaired fetal and neonatal growth.

2. Of a drug: applied to the surface of the skin, typically in the form of an ointment, gel, or impregnated adhesive patch, so as to allow gradual absorption into the body; relating to or used in this method of drug delivery.

ΚΠ

1976 Aviation, Space & Environm. Med. 47 1096 A double-blind placebo-controlled study compared the efficacy of the antimotion sickness drug scopolamine when administered by oral or transdermal routes.

1982 Fortune (Nexis) 14 June 105 The long-awaited transdermal patches are ‘a medical breakthrough’.

1998 Esquire Feb. 70/1 On my desk is a box of patches, a nicotine transdermal system, step one, twenty-one milligrams.

2003 S. J. Segal & L. Mastroianni Hormone Use Menopause & Male Andropause 99 The transdermal gel quickly took over the lion's share of the testosterone supplementation market.

2005 Chicago Tribune (Midwest ed.) 13 Feb. xiii. 8/5 Transdermal skin patches, which stick like bandages as they deliver medications, have several advantages over pills.

Derivatives

transˈdermally adv. through or across the skin; by absorption through the skin.

ΚΠ

1942 Laryngoscope 52 31 Patients..were treated by interstitial radon in the form of gold seeds, either inserted transdermally or after surgical exposure of the tumor.

1976 Aviation, Space & Environ. Med. 47 1096/2 The chief purpose of the present report is to compare the results of administering scopolamine orally and by a device that permits absorption, transdermally, directly into the circulation.

2008 A. Davies Mine All Mine 12 I inject them, breathe them, swallow them, transdermally patch them.

This is a new entry (OED Third Edition, December 2009; most recently modified version published online March 2022).

单词	transdermal
释义	transdermaladj. Brit. /tranzˈdəːml/, /trɑːnzˈdəːml/, /transˈdəːml/, /trɑːnsˈdəːml/, U.S. /trænzˈdərm(ə)l/, /træn(t)sˈdərm(ə)l/ Origin: Formed within English, by derivation. Etymons: trans- prefix, dermal adj. Etymology: < trans- prefix + dermal adj. Medicine. 1. Passing, occurring, or effected through or across the skin. ΚΠ 1907 T. W. Jackson Trop. Med. ii. iv. 423 This hypothesis of transdermal miracidium-infection requires proof. 1916 T. W. Brophy Oral Surg. I. viii. 122 In wounds about the face, transdermal stitches should be passed only through the corium. 1969 Acta Otolaryngol. 67 69 (title) Hearing rehabilitation by means of transdermal electrotherapy. 1988 New Scientist 7 Apr. 26/3 Transdermal potential, a voltage between the outer layers of the skin and the tissues below, is the key to solving the problem. 2001 J. M. Ntambi & Y.-C. Kim in N. Moustaïd-Moussa & C. D. Berdanier Nutrient–Gene Interactions in Health & Dis. iii. 52 Increased transdermal water loss, and impaired fetal and neonatal growth. 2. Of a drug: applied to the surface of the skin, typically in the form of an ointment, gel, or impregnated adhesive patch, so as to allow gradual absorption into the body; relating to or used in this method of drug delivery. ΚΠ 1976 Aviation, Space & Environm. Med. 47 1096 A double-blind placebo-controlled study compared the efficacy of the antimotion sickness drug scopolamine when administered by oral or transdermal routes. 1982 Fortune (Nexis) 14 June 105 The long-awaited transdermal patches are ‘a medical breakthrough’. 1998 Esquire Feb. 70/1 On my desk is a box of patches, a nicotine transdermal system, step one, twenty-one milligrams. 2003 S. J. Segal & L. Mastroianni Hormone Use Menopause & Male Andropause 99 The transdermal gel quickly took over the lion's share of the testosterone supplementation market. 2005 Chicago Tribune (Midwest ed.) 13 Feb. xiii. 8/5 Transdermal skin patches, which stick like bandages as they deliver medications, have several advantages over pills. Derivatives transˈdermally adv. through or across the skin; by absorption through the skin. ΚΠ 1942 Laryngoscope 52 31 Patients..were treated by interstitial radon in the form of gold seeds, either inserted transdermally or after surgical exposure of the tumor. 1976 Aviation, Space & Environ. Med. 47 1096/2 The chief purpose of the present report is to compare the results of administering scopolamine orally and by a device that permits absorption, transdermally, directly into the circulation. 2008 A. Davies Mine All Mine 12 I inject them, breathe them, swallow them, transdermally patch them. This is a new entry (OED Third Edition, December 2009; most recently modified version published online March 2022). < adj.1907
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