thymidylicadj.

/θʌɪmɪˈdɪlɪk/

Etymology: < thymidine n. + -yl suffix + -ic suffix.

Biochemistry.

thymidylic acid n. any phosphoric acid ester of thymidine, C₅H₈O₂(PH₂O₄).C₅H₄N₂O₂, one or other of which is one of the four nucleotides present in most DNA.

ΚΠ

1951 Jrnl Bacteriol. 61 41 Samples of thymidylic acid, desoxyadenylic acid..and desoxyguanylic acid..were made available.

1968 A. White et al. Princ. Biochem. (ed. 4) ix. 186 Deoxyguanylic, thymidylic, and deoxycytidylic acids esterified at positions 3′ and 5′ are also found in hydrolysates of DNA.

1972 Sci. Amer. Dec. 85/1 Until well into the 1930's DNA was generally thought to be merely a tetranucleotide composed of one unit each of adenylic, guanylic, thymidylic and cytidylic acids.

Derivatives

thyˈmidylate n. the anion derived from thymidylic acid by the loss of a hydrogen atom from the phosphate group.

ΘΚΠ

the world > matter > chemistry > organic chemistry > salts, esters or anions of organic acids > [noun]

hydrochloride1823

isethionates1838

citraconate1840

adipate1841

anthranilate1841

stearate1841

itaconic acid1842

salicylate1842

oenanthate1845

ammelide1846

pelargonate1848

pelargyl1851

melanuric acid1852

methylate1852

opianyl1852

abietate1853

maleate1853

fulminuric1856

glyoxylate1856

urethane1856

indican1859

oxalyl1859

malonate1862

methacrylate1865

amylate1866

acetoacetate1873

isobutyrate1873

glutamate1876

hydrobromide1877

nicotinate1879

isovalerate1882

calcium gluconate1884

methoxide1885

isophthalate1886

homogentisate1891

naphthenate1899

peracetate1901

iodoacetate1902

glucuronate1904

hydnocarpate1905

thiomalate1905

azide1907

phytate1908

linolenate1909

isocitrate1925

phenylpyruvate1926

monosodium glutamate1929

perester1933

phosphonate1934

polymethacrylate1935

pantothenate1938

phosphoenolpyruvate1941

nylon salt1945

pantoate1945

penicilloate1946

thymidylate1959

chorismate1965

nonanoate1965

neuraminate1970

1959 Flaks & Cohen in Jrnl. Biol. Chem. 234 2981/1 We are designating the latter catalytic activity..as ‘thymidylate synthetase’.

1974 J. W. Drake in M. J. Carlile & J. J. Skehel Evol. in Microbial World 51 The td gene encodes the viral thymidylate synthetase.

This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).

单词	thymidylic
释义	thymidylicadj. /θʌɪmɪˈdɪlɪk/ Etymology: < thymidine n. + -yl suffix + -ic suffix. Biochemistry. thymidylic acid n. any phosphoric acid ester of thymidine, C₅H₈O₂(PH₂O₄).C₅H₄N₂O₂, one or other of which is one of the four nucleotides present in most DNA. ΚΠ 1951 Jrnl Bacteriol. 61 41 Samples of thymidylic acid, desoxyadenylic acid..and desoxyguanylic acid..were made available. 1968 A. White et al. Princ. Biochem. (ed. 4) ix. 186 Deoxyguanylic, thymidylic, and deoxycytidylic acids esterified at positions 3′ and 5′ are also found in hydrolysates of DNA. 1972 Sci. Amer. Dec. 85/1 Until well into the 1930's DNA was generally thought to be merely a tetranucleotide composed of one unit each of adenylic, guanylic, thymidylic and cytidylic acids. Derivatives thyˈmidylate n. the anion derived from thymidylic acid by the loss of a hydrogen atom from the phosphate group. ΘΚΠ the world > matter > chemistry > organic chemistry > salts, esters or anions of organic acids > [noun] hydrochloride1823 isethionates1838 citraconate1840 adipate1841 anthranilate1841 stearate1841 itaconic acid1842 salicylate1842 oenanthate1845 ammelide1846 pelargonate1848 pelargyl1851 melanuric acid1852 methylate1852 opianyl1852 abietate1853 maleate1853 fulminuric1856 glyoxylate1856 urethane1856 indican1859 oxalyl1859 malonate1862 methacrylate1865 amylate1866 acetoacetate1873 isobutyrate1873 glutamate1876 hydrobromide1877 nicotinate1879 isovalerate1882 calcium gluconate1884 methoxide1885 isophthalate1886 homogentisate1891 naphthenate1899 peracetate1901 iodoacetate1902 glucuronate1904 hydnocarpate1905 thiomalate1905 azide1907 phytate1908 linolenate1909 isocitrate1925 phenylpyruvate1926 monosodium glutamate1929 perester1933 phosphonate1934 polymethacrylate1935 pantothenate1938 phosphoenolpyruvate1941 nylon salt1945 pantoate1945 penicilloate1946 thymidylate1959 chorismate1965 nonanoate1965 neuraminate1970 1959 Flaks & Cohen in Jrnl. Biol. Chem. 234 2981/1 We are designating the latter catalytic activity..as ‘thymidylate synthetase’. 1974 J. W. Drake in M. J. Carlile & J. J. Skehel Evol. in Microbial World 51 The td gene encodes the viral thymidylate synthetase. This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018). < adj.1951
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