thrombusn.

1676 J. Davies in tr. S. Santorio Medicina Statica 45 They who conceive the blackness of the spots [of the plague] to be a sign of adustion, are mistaken; for many times aged men, being..without any feaver, depart this life in two days time, with the same blackness, but proceeding from a Thrombus, or clots of blood.

1699 tr. de La Vauguion Compl. Body Chirurg. Operations xxiv. 129 Sometimes there happens to be a small Collection of Blood under the Skin, which forms a Thrombus, and after a little Inflammation and Pain, ends in a slight Suppuration.

1746 S. Mihles Elements Surg. 185 A tolerable large Orifice is always preferable to a small one, as the last, especially when the Incision is near a Valve, is commonly attended with a Thrombus.

1786 R. White Present Pract. Surg. 172 A portion of it [sc. the stream of blood] is forced between the skin and cellular membrane, so as to raise a small tumour over the orifice in the vein, which is called Thrombus.

1842 Provinc. Med. & Surg. Jrnl. 2 423/1 The operation [sc. opening the vena magna ipsius penis] is, with ordinary care, an easy one, but unless cautiously performed, a thrombus may occur.

1886 Lancet 30 Oct. 806/1 When hæmorrhage into the broad ligament has occurred, the arrest of the hæmorrhage has been brought about by nature's own methods,..and therefore all we have to do with is the thrombus.

1916 G. P. Shears Obstetrics xv. 321 When the placenta is retained its rough surface favors the coagulation of the blood which comes in contact with it and the result may be a thrombus, which gradually increases in size until it fills the uterine cavity.

1725 J. Freind Hist. Physick I. 196 In the aneurysm, upon dissection, were found, besides fluid blood, two or three pounds of Thrombi, which lay like so many plates upon one another.

1733 D. Turner Anc. Physician's Legacy 4 Upon opening the Body..the right Auricle of the Heart was prodigiously distended, and filled with Thrombus.

1771 W. Hewson in Philos. Trans. 1770 (Royal Soc.) 60 382 Thence probably is the origin of those laminated thrombi met with in such sacks [sc. aneurysms].

1846 Lancet 16 May 555/1 The metamorphoses of the thrombus, or clot of blood which forms in a vessel above a part at which it is tied.

1873 C. H. Ralfe Outl. Physiol. Chem. 16 A thrombus blocks up a cerebral artery, and acute softening of the cerebral substance supplied by that artery is the result.

1901 W. Osler Princ. & Pract. Med. (ed. 4) i. 12 Inflammation of the arteries with thrombus formation has been frequently described in typhoid fever.

1961 R. D. Baker Essent. Pathol. v. 82 There is danger of a portion of the thrombus breaking loose and passing as an embolus to the pulmonary artery and lungs.

1970 R. Passmore & J. S. Robson Compan. Med. Stud. II. xxvi. 3/1 In large vessels, the thrombus usually remains plastered as a plaque against the wall of the vessel, whereas in small arteries continuation of the process may lead to an occlusive thrombus which blocks completely the direct blood flow.

2001 Times 1 Nov. ii. 9/2 This clot (or thrombus) may then block a coronary artery and subsequently cause a coronary thrombosis.

1895 I. K. Funk et al. Standard Dict. Eng. Lang. II. at Thrombus Milk-thrombus, a knotty tumor in the female breast during lactation, due to the arrest and accumulation of milk in the lactiferous ducts.

1904 Encycl. Americana XV. at Thrombus Of late the term has been applied (milk thrombus), to an accumulation of curdled milk in a lacteriferous tube.