thrombinn.

Brit.

/ˈθrɒmbɪn/, U.S.

/ˈθrɑmbən/

Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: thrombo- comb. form, -in suffix¹.

Etymology: < thrombo- comb. form + -in suffix¹, after German Thrombin ( A. Schmidt Zur Blutlehre (1892) xii. 202).

Biochemistry.

An enzyme that converts fibrinogen to fibrin in the process of blood clotting.

ΚΠ

1897 Edinb. Med. Jrnl. 1 332 This body [sc. prothrombin] is transformed into fibrin ferment or thrombin, by means of soluble calcium salts.

a1933 J. A. Thomson Biol. for Everyman (1934) II. 933 Some investigators rank among enzymes a substance called thrombin, which has to do with forming the fixed fibrin out of a soluble protein, fibrinogen.

1968 New Eng. Jrnl. Med. 4 Apr. 793/2 Thrombin cleaves the long, axially oriented fibrinogen molecule at a specific site, liberating two peptides from the molecule.

2011 N.Y. Times (National ed.) 29 Aug. b3/6 Pradaxa inhibits thrombin, an enzyme in clot formation.

This entry has been updated (OED Third Edition, March 2017; most recently modified version published online June 2022).

单词	thrombin
释义	thrombinn. Brit. /ˈθrɒmbɪn/, U.S. /ˈθrɑmbən/ Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: thrombo- comb. form, -in suffix¹. Etymology: < thrombo- comb. form + -in suffix¹, after German Thrombin ( A. Schmidt Zur Blutlehre (1892) xii. 202). Biochemistry. An enzyme that converts fibrinogen to fibrin in the process of blood clotting. ΚΠ 1897 Edinb. Med. Jrnl. 1 332 This body [sc. prothrombin] is transformed into fibrin ferment or thrombin, by means of soluble calcium salts. a1933 J. A. Thomson Biol. for Everyman (1934) II. 933 Some investigators rank among enzymes a substance called thrombin, which has to do with forming the fixed fibrin out of a soluble protein, fibrinogen. 1968 New Eng. Jrnl. Med. 4 Apr. 793/2 Thrombin cleaves the long, axially oriented fibrinogen molecule at a specific site, liberating two peptides from the molecule. 2011 N.Y. Times (National ed.) 29 Aug. b3/6 Pradaxa inhibits thrombin, an enzyme in clot formation. This entry has been updated (OED Third Edition, March 2017; most recently modified version published online June 2022). < n.1897
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