achondroplasian.

Brit.

/əˌkɒndrəˈpleɪzɪə/,

/ˌeɪkɒndrəˈpleɪzɪə/,

/əˌkɒndrəˈpleɪʒə/,

/ˌeɪkɒndrəˈpleɪʒə/, U.S.

/ˌeɪˌkɑndrəˈpleɪʒ(i)ə/,

/ˌeɪˌkɑndrəˈpleɪziə/

Origin: A borrowing from Greek, combined with English elements; modelled on a French lexical item. Etymons: a- prefix⁶, Greek χόνδρος , -plasia comb. form.

Etymology: < a- prefix⁶ + ancient Greek χόνδρος cartilage (see chondro- comb. form) + -plasia comb. form, after French achondroplasie (J. Parrot 1878, in Bull. de la Soc. d'Anthropol. de Paris 1 297). Compare ancient Greek ἄχονδρος without cartilage.

Medicine.

A heritable (autosomal dominant) form of dwarfism which results from defective conversion of cartilage into bone, and is characterized by shortening of the long bones of the limbs, often with enlargement of the head and midfacial hypoplasia. Also: any of a group of similar disorders in various breeds of domestic animal.

ΘΚΠ

the world > health and disease > ill health > deformity > [noun] > imperfect development

untowardness1538

agenesis1827

stasimorphy1869

achondroplasia1888

undergrowth1891

infantilism1895

ateleiosis1902

1888 Lancet 22 Dec. 1231/1 He thought the condition present was that described by Parrot as ‘achondroplasia’.

1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 11 Osteopsathyrosis, chondrodystrophia, periosteal aplasia, and achondroplasia are terms which, whilst descriptive enough of certain cases, are quite inappropriate for others.

1921–2 C. R. Stockard in Harvey Lect. 17 i. 43 Achondroplasia occurs in various degrees among several of the domesticated species, but the most varied and remarkable examples of the condition exist among the fancy breeds of dogs.

1957 Amarillo (Texas) Globe-Times 15 July 16/1 There is another type of achondroplasia which can run through several generations of a family.

1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. ii. xlv. 47/1 Osteogenesis imperfecta congenita is easily distinguished from achondroplasia but unnaturally short limbs, the result of prenatal fractures, create a superficial resemblance.

2004 R. Hutchinson For Love of Dachshunds ii. 28/1 We look first at the species contrast between achondroplasia as a singular syndrome in human beings and as a manifold of separable traits in dogs.

Derivatives

achondroˈplasiac n. and adj. = achondroplastic adj. and n.

ΚΠ

1893 Trans. Edinb. Obstetr. Soc. 18 199 He had secured photographs of the two adult achondroplasiacs.

1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 12 An achondroplasiac mother may give birth to an achondroplasiac infant.

1968 Lancet 18 July 103/1 The achondroplasiacs of Velasquez.

a2000 W. D. Hamilton Narrow Roads of Gene Land (2001) II. xii. 502 (note) Couples who are both achondroplasiac dwarfs.

This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021).

单词	achondroplasia
释义	achondroplasian. Brit. /əˌkɒndrəˈpleɪzɪə/, /ˌeɪkɒndrəˈpleɪzɪə/, /əˌkɒndrəˈpleɪʒə/, /ˌeɪkɒndrəˈpleɪʒə/, U.S. /ˌeɪˌkɑndrəˈpleɪʒ(i)ə/, /ˌeɪˌkɑndrəˈpleɪziə/ Origin: A borrowing from Greek, combined with English elements; modelled on a French lexical item. Etymons: a- prefix⁶, Greek χόνδρος , -plasia comb. form. Etymology: < a- prefix⁶ + ancient Greek χόνδρος cartilage (see chondro- comb. form) + -plasia comb. form, after French achondroplasie (J. Parrot 1878, in Bull. de la Soc. d'Anthropol. de Paris 1 297). Compare ancient Greek ἄχονδρος without cartilage. Medicine. A heritable (autosomal dominant) form of dwarfism which results from defective conversion of cartilage into bone, and is characterized by shortening of the long bones of the limbs, often with enlargement of the head and midfacial hypoplasia. Also: any of a group of similar disorders in various breeds of domestic animal. ΘΚΠ the world > health and disease > ill health > deformity > [noun] > imperfect development untowardness1538 agenesis1827 stasimorphy1869 achondroplasia1888 undergrowth1891 infantilism1895 ateleiosis1902 1888 Lancet 22 Dec. 1231/1 He thought the condition present was that described by Parrot as ‘achondroplasia’. 1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 11 Osteopsathyrosis, chondrodystrophia, periosteal aplasia, and achondroplasia are terms which, whilst descriptive enough of certain cases, are quite inappropriate for others. 1921–2 C. R. Stockard in Harvey Lect. 17 i. 43 Achondroplasia occurs in various degrees among several of the domesticated species, but the most varied and remarkable examples of the condition exist among the fancy breeds of dogs. 1957 Amarillo (Texas) Globe-Times 15 July 16/1 There is another type of achondroplasia which can run through several generations of a family. 1974 R. Passmore & J. S. Robson Compan. Med. Stud. III. ii. xlv. 47/1 Osteogenesis imperfecta congenita is easily distinguished from achondroplasia but unnaturally short limbs, the result of prenatal fractures, create a superficial resemblance. 2004 R. Hutchinson For Love of Dachshunds ii. 28/1 We look first at the species contrast between achondroplasia as a singular syndrome in human beings and as a manifold of separable traits in dogs. Derivatives achondroˈplasiac n. and adj. = achondroplastic adj. and n. ΚΠ 1893 Trans. Edinb. Obstetr. Soc. 18 199 He had secured photographs of the two adult achondroplasiacs. 1899 J. W. Ballantyne in W. A. Edwards Cycl. Dis. Children V. 12 An achondroplasiac mother may give birth to an achondroplasiac infant. 1968 Lancet 18 July 103/1 The achondroplasiacs of Velasquez. a2000 W. D. Hamilton Narrow Roads of Gene Land (2001) II. xii. 502 (note) Couples who are both achondroplasiac dwarfs. This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021). < n.1888
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