thio-comb. form

1854 Kekulé in Proc. Royal Soc. 7 38 Thiacetic Acid,—Sulphuretted Acetic Acid—has been obtained by me by acting on monohydrated acetic acid with tersulphide of phosphorus.

1847 Wöhler & Liebig in Mem. Chem. Soc. III. 303 A new organic alkali free from oxygen..which we call thialdine..contracted from θεῖον and aldehyde.

1881 H. Watts Dict. Chem. VIII. 1952 Thiamides..may be conveniently prepared by the action of phosphorus sulphide..on amides.

1893 Jrnl. Soc. Chem. Industry 31 Jan. 4 The original colour quickly reappears on exposure to air: Azine-, Oxazine-, Thiazine-, and Acridine-Colours.

1971 R. L. M. Allen Colour Chem. viii. 130 Thiazine dyes are used on cellulosic fibres, silk, bast fibres, leather and paper.

1888 Hantzsch & Weber in Jrnl. Chem. Soc. LIV. 256 Thiazole is the name given to [these] isomeric compounds.

1888 Hantzsch & Weber in Jrnl. Chem. Soc. LIV. 574 Thioamides condense with α-halogen-substituted ketones to form thiazoles.

1956 I. L. Finar Org. Chem. II. xii. 451 A general method for preparing thiazoles is the condensation between α-halogenocarbonyl compounds..and thioamides.

1885 Peter Jrnl. Chem. Soc. XLVIII. 141 ThiënylmethylacetoximeC₄H₃S.CMe:NOH..forms a white crystalline mass.

1882 Will Jrnl. Chem. Soc. XLII. 1088 Thiocarbamates... A continuation of the author's researches.

1878 Guareschi Jrnl. Chem. Soc. XXXIV. 860 Thiocarbamide CS (NH₂)₂[etc.] when oxidised by permanganate likewise yield all their sulphur in the state of sulphuric acid.

1891 Internat. Ann. Anthonys Photogr. Bull. 397 Prof. J. E. Reynolds, who was the original discoverer of the rinsing sulphur urea, now known as thio-carbamide.

1883 Jrnl. Chem. Soc. 44 405 The use of potassium thiocarbonate as a remedy against phylloxera.

1887 Jrnl. Chem. Soc. 51 272 The conversion of thiocarbonyl chloride into thiocarbonyl tetrachloride by the assimilation of two atoms of chlorine takes place at ordinary temperatures.

1929 Bull. Chem. Soc. Japan 4 176 Thio-choline bromide was prepared by heating bromocholine bromide with 2-thio-uracil or 4-methyl-2-thio-uracil with water.

1980 Sci. Amer. Apr. 37/3 Nerve gas in the sampled air inhibits the enzyme, just as it would in the human body, resulting in a drop in the thiocholine level, which triggers the alarm.

1877 Jrnl. Chem. Soc. 32 869 Thiocyanates of the acid radicles are prepared by the action of acid chlorides on dry lead thiocyanate.

1877 Jrnl. Chem. Soc. 32 423 Action of Nascent Thiocyanic Acid on Alcohol.

1952 Jrnl. Biol. Chem. 196 545 These results thus confirm the conclusions of Lynen and Reichert that the acetyl group of acetyl CoA is attached, in thioester linkage, to the thioethanolamine portion of the CoA molecule.

1979 Nature 1 Mar. 86/1 The role of ATP and other energy-rich phosphates is considered in detail and this is followed by a study of thioesters including coenzyme A derivatives.

1889 G. M'Gowan tr. A. Bernthsen Text-bk. Org. Chem. iv. 94 The Thio-ethers, also termed alkyl sulphides, e.g. ethyl sulphide, (C₂H₅)₂S, are..neutral volatile liquids.

1979 Nature 20 Dec. 808/2 Each haem is linked, as in cytochrome c, to the apoprotein by two thioether bonds.

1857 Jrnl. Chem. Soc. 9 185 Thioformic acid crystallises from formic acid, or from boiling alcohol, in slender needles.

1877 Jrnl. Chem. Soc. 32 595 Potassium thioglycollate..crystallises in masses of small needles, and is readily soluble in water and alcohol.

1976 Nature 24 June 652/1 Much early work was concerned with the evaluation of different methods for breaking disulphide bonds, and procedures were developed using..sodium thioglycollate.

1980 A. L. Smith Microbiol. & Pathol. (ed. 12) v. 64/1 Thioglycollate broth, a special medium containing thioglycollic acid, supports the growth of anaerobes..without special seal.

1877 Jrnl. Chem. Soc. 32 595 Carius obtained an acid of the formula H.C₂H₂(HS)O₂, which he called monosulphoglycollic acid. Some uncertainty was attached, however, to the constitution of the product of this reaction, and the author now shows that both thioglycollic acid, H.C₂H₂(HS)O₂, and thiodiglycollic acid..are produced.

1889 G. M'Gowan tr. A. Bernthsen Text-bk. Org. Chem. Index 542/1 Thio-ketones.

1965 New Scientist 30 Dec. 921/2 The thioketones (compounds containing the > C = S group) are in general red oils with intense nauseating smells.

1878 Chem. News 20 Dec. 294/2 (heading) Notes on certain thionates.

1938 Thorpe's Dict. Appl. Chem. (ed. 4) II. 574/2 All thionates are decomposed by heat, yielding generally sulphates, sulphur dioxide, and, except with dithionates, sulphur.

1880 Jrnl. Chem. Soc. 37 593 A qualitative reaction, by which pentathionic acid is clearly distinguished from any other of the thionic acids.

1886 Jrnl. Chem. Soc. 50 53 The addition of strong hydrochloric acid does not turn the solution blue, as is the case with thionine.

1956 Thorpe's Dict. Appl. Chem. (ed. 4) XI. 590/1 Lauth had already indicated that bright blue dyes could be obtained by methylating thionine but such a process was not economic.

1976 Nature 1 Jan. 60/2 Feulgen reaction carried out on the specimens treated with..thionin and exposed to light gave differential staining.

1838 Brit. Ann. & Epitome Progress Sci. 1839 377 Thionurate of zinc.

1838 Brit. Ann. & Epitome Progress Sci. 1839 377 Thionuric acid.

1874 H. Watts Dict. Chem. V. 779 Thionuric acid..forms a crystalline mass, consisting of fine needles.

1866 Chem. News 9 Mar. 117/1 M. Wurtz presented a note ‘On the Synthesis of Chloride of Thionyle’.

1874 H. Watts Dict. Chem. V. 780 Thionyl. SO.—The radicle of the sulphurous compounds: e.g., sulphurous chloride, (SO)″Cl₂ = chloride of thionyl.

1883 Meyer in Jrnl. Chem. Soc. XLIV. 1091 A substance contained in Coal-tar Benzene..to which the author has given the name of thiophene.

1903 A. J. Walker & O. E. Mott tr. A. F. Holleman Text-bk. Org. Chem. 500 Thiophen can be synthesized by various methods, the most important being the interaction of succinic acid and pentasulphide of phosphorus.

1932 I. D. Garard Introd. Org. Chem. xiii. 183 Coal tar benzene always contains thiophene, C₄H₄S, which boils at 85° and is therefore not readily removed by distillation.

1951 Engineering 23 Nov. 667/3 Thiophen cannot be removed from [town] gas by any practical chemical method.

1967 M. J. Janssen Organosulfur Chem. i. 10 Benzene derivatives are much less readily hydrogenated than thiophene.

1899 New Sydenham Soc. Lexicon Thiophenol,..phenyl mercaptan.

1899 New Sydenham Soc. Lexicon Thioresorcin,..a popular substitution of resorcin... Used as a dusting powder.

1894 Jrnl. Chem. Soc. 66 i. 76 (heading) Derivatives of thiosemicarbazide.

1971 Chem. Abstr. 74 74835 Thiosemicarbazide..given i.p. to mice did not affect the incorporation of intraventricularly administered..putrescine-2HCl..into γ-aminobutyric acid in the brain.

1902 Jrnl. Chem. Soc. 82 572 The thiosemicarbazones of aldehydes and ketones readily yield insoluble copper, silver and mercury derivatives, which can be used for the purpose of isolating these compounds.

1979 Cancer Res. 39 4601/1 The isoquinoline thiosemicarbazone derivatives have been shown to be potent inhibitors of ribonucleotide reductase.

1853 A. Ure Dict. Arts (ed. 4) I. 32 Thiosinnamine.

1881 Piesse & Stansell in Jrnl. Chem. Soc. XL. 207 Thiosinamine is an oily substance at 100°, but gradually solidifies when cold.

1873 H. B. Jones & H. Watts Fownes's Man. Elem. Chem. (ed. 11) 198 The solution of a thiosulphate.

1874 Jrnl. Chem. Soc. 27 771 The close relation between the thiosulphates and sulphates is shown by the formulæ—SO₂^SNa_ONa and SO₂^ONa_ONa.

1868 H. Watts Fownes's Man. Elem. Chem. (ed. 10) 214 Thiosulphuric Acid..is scarcely known.

1874 Jrnl. Chem. Soc. 27 770 On the Constitution of Hyposulphurous (Thiosulphuric) Acid.

1953 Arch. Internal Med. 92 629 The purpose of this communication is to present our preliminary experience in the treatment of..human leukemias..with triethylene thiophosphoramide (ThioTEPA).

1976 Nature 13 May 135/1 Criticism of the use of the alkylating agent thiotepa (triethylene thiophosphoramide) to sterilise mosquitoes, as part of an eradication programme in India, focused on its toxicity and the possibility that it or its breakdown products would harm other animal components of the food chain.

1885 Jrnl. Chem. Soc. 48 251 A Simple Method of obtaining Thiotolene.

1905 Wheeler & Bristol in Amer. Chem. Jrnl. 33 458 2-Thiouracil... This compound was first obtained.. when pseudoethylthiourea, containing some thiourea, was condensed with ethyl sodium formylacetate.

1977 Martindale's Extra Pharmacopœia (ed. 27) 304/1 Thiouracil was formerly used in the control and treatment of thyrotoxicosis and in the preparation of patients for thyroidectomy.

1894 H. F. Morley & M. M. P. Muir Watts' Dict. Chem. (rev. ed.) IV. 710 Formed by adding Br to an alcoholic or cold aqueous solution of thio-urea.

1911 Jrnl. Chem. Soc. 99 145 In order to obtain this sulphoxide [sc. diphenylmethane o-sulphoxide], thioxanthen was oxidised with hydrogen dioxide in acetic anhydride solution.

1924 ‘Chem. Age’ Chem. Dict. 148/2 Thioxanthenes, derivatives of thioxanthene.

1945 Jrnl. Chem. Soc. 659 (heading) Action of oxygen in sunlight on thioxanthen.

1885 Jrnl. Chem. Soc. 48 251 A simple method of obtaining..thioxylene.

1952 Lancet 1 Mar. 436/2 Para-acetamidobenzaldehyde Thiosemicarbazone. [Note] This substance..is marketed under various names;..thiacetazone, &c.

1976 MacGillivray & Hall in G. S. Avery Drug Treatment xiv. 382/2 Massive breast enlargement has been seen with isoniazid regimens containing thiacetazone.

1951 Biol. Abstr. 25 811/2 It was possible to isolate thiobacilli capable of changing hyposulfides into sulfates.

1973 Nature 11 May 99/2 Thiobacilli, iron bacteria and algae can survive in acidic water of about pH 2.

1900 A. C. Jones tr. A. Fischer Struct. & Functions Bacteria 65 The sulphur bacteria, Thiobacteria, whose cells are often crammed full of spherical refringent masses of pure sulphur, occur in nature in places where free sulphuretted hydrogen is present.

1900 A. C. Jones tr. A. Fischer Struct. & Functions Bacteria 65 Thiobacteria can be found at any time of the year, but are most abundant in the early spring and late autumn.

1899 New Sydenham Soc. Lexicon Thiocamph..on exposure evolves sulphur dioxide in steady fumes.

1935 Chem. Abstr. 29 6242 When crude lactoflavin is made alk., the fluorescence changes from yellowish green to blue. This phenomenon is due to the presence of a S-contg. pigment for which the name thiochrome is proposed.

1963 Steyn-Parvé & Monfoort in Florkin & Stotz Comprehensive Biochem. XI. i. 16 The thiochrome method is based on the observation..that oxidation with alkaline ferricyanide converts thiamine into a compound with intense blue fluorescence: thiochrome... The thiochrome is extracted..and the fluorescence of the extract measured.

1899 New Sydenham Soc. Lexicon Thioform..a light yellowish powder, without odour or taste..has..been introduced into surgery with promising success.

1910 Brickdale Guide Newer Remedies 60 A dithiosalicylate..has been..named Thioform.

1930 Official Gaz. (U.S. Patent Office) 20 May 555/2 Thiokol for sulfur-containing plastic material used in the manufacture of gaskets,..protective coatings, and like products.

1936 Industr. & Engin. Chem. Mar. 275/1 Various olefin-polysulfide reaction products.., under the trade name of Thiokols, have been presented to the industry.

1943 Trade Marks Jrnl. 8 Dec. 525/1 Thiokol... Thermo-setting or thermo-plastic condensation products of the nature of rubber, being compounds of or containing sulphur, and articles (not included in other Classes) made therefrom. Thiokol Corporation.., Trenton, New Jersey.

1972 Materials & Technol. V. xiv. 491 All thiokols are originally obtained in latex form, and as such they have found some industrial applications as an impregnant for textiles and leather.

1894 J. P. Remington Pract. Pharmacy (ed. 3) 1433 Thiolin. Salts of thiosulphonic acid. Salt of thiolinic acid. Sulphonated and sulphurated linseed oil.

1899 New Sydenham Soc. Lexicon Thiolin, thiolinic acid.

1958 Brit. Pharmacopœia 675 Thiomersal should be protected from light.

1968 Wilson & Schild Appl. Pharmacol. (ed. 10) xxxvi. 671 Phenylmercuric nitrate, thiomersal (merthiolate), and other organic mercurials, have a better therapeutic index than mercuric chloride.

1964 B.S.I. News Mar. 23 Thionazin.

1974 Martin & Worthing Pesticide Man. (Brit. Crop Protection Council) (ed. 4) 488 Thionazin is a soil insecticide and nematicide effective against..nematodes,..root maggots and..aphids.

1959 Jrnl. Pharmacol. & Exper. Therapeutics 126 312 (heading) Some neuro~pharmacological properties of thioridazine hydrochloride (Mellaril).

1899 New Sydenham Soc. Lexicon Thiosa·piol, a sulphuretted soap, containing 10 per cent. of sulphur, obtained by heating sulphur and oleic acid together... A successful application to many skin diseases.

1965 Simpson & Iqbal in Current Therapeutic Res. VII. 697 (heading) A preliminary study of thiothixene in chronic schizophrenics.

1976 J. R. Smythies & L. Corbett Psychiatry Students of Med. x. 194 Thiothixene is a potent and effective antipsychotic agent in acute and chronic schizophrenia.