Thorotrastn.
/ˈθɔːrə(ʊ)trɑːst//ˈθɔːrə(ʊ)trast/ Medicine.
A colloidal solution of thorium dioxide formerly used as a contrast medium in radiography. A proprietary name in the U.S.
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the world > health and disease > healing > diagnosis or prognosis > radiography or radiology > [noun] > equipment used in > contrast medium
iodipin1899
Lipiodol1923
Thorotrast1932
iodopyracet1947
iodipamide1955
1932 Official Gaz. (U.S. Patent Office) 5 Apr. 14/2 Heyden Chemical Corporation, New York... Thorotrast for medicinal preparation finding its application in the photography by X-rays for medicinal and similar purposes.
1933 A. Egas Moniz in Lancet 18 Nov. 1147/1 The speed of circulation is very different in the brain as compared with other parts of the head... We have ascertained this fact by studying the arteriograms and phlebograms of diverse cases, but confirmation was obtained by a series of angiograms, taken from second to second, after the injection of thorotrast in the common carotid and the external and internal carotids.
1947 Radiology 49 362/2 The fact that ‘thorotrast’ (a colloidal suspension of thorium dioxide) is frequently used in human diagnostic work.
1976 P. Collard Devel. Microbiol. x. 136 Animals were injected intravenously with particulate materials, indian ink, colloidal iron or thorotrast.
1977 Lancet 18 June 1297/1 The main long-term sequelæ of thorotrast are local effects and tumours at the site of injection and/or deposit..and fatal blood dyscrasias, including leukæmia and aplastic anæmias.
This entry has not yet been fully updated (first published 1986; most recently modified version published online December 2020).
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n.1932