tamoxifenn.
/təˈmɒksɪfɛn/ Pharmacology.
An œstrogen antagonist, (CH3)2N(CH2)2·O·C6H4·(C6H5)C:C(C6H5)·CH2CH3, used to treat breast cancer and infertility in women.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for cancer or leukemia
amethopterin1948
Myleran1952
Laetrile1953
thioguanine1953
thioTEPA1953
mercaptopurine1954
methotrexate1955
busulfan1956
chlorambucil1956
cyclophosphamide1960
vinblastine1962
vincristine1962
levamisole1969
vinca alkaloid1970
doxorubicin1971
tamoxifen1972
Airol1974
trastuzumab1997
thiotepa-
1972 Approved Names 1970 (Brit. Pharmacopœia Comm.) Suppl. iv. 6 Tamoxifen.
1972 Clin. Endocrinol. I. 275 A derivative of triphenylethylene was examined by Harper & Walpole (1967a,b) for its anti-oestrogenic activity in rats. This compound..was subsequently named tamoxifen.
1980 Brit. Med. Jrnl. 29 Nov. 1459/1 Lung metastases then enlarged and tamoxifen was substituted but discontinued after only two months because of progressive disease.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1972