sulphonylureasulfonylurean.
Pharmacol.
Any of the group of hypoglycæmic drugs containing the active grouping SO2·NH·CO·NH, which are used orally in the treatment of diabetes.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for diabetes
synthalin1927
protamine insulin1935
protamine zinc insulin1935
Ultralente1953
sulphonylurea1956
tolbutamide1956
phenformin1959
acetohexamide1961
metformin1961
tolazamide1963
1956 Science 6 Apr. 583/2 A statistically highly significant hypoglycemic response occurred in 34 of the patients with diabetes who were given the sulfonylurea.
1966 New Scientist 24 Nov. 433/1 The longing of diabetics for a hypoglycaemic drug which could be taken orally..was realized ten years ago when the sulphonylureas and diguanides were introduced.
1974 M. C. Gerald Pharmacol. xxv. 442 The oral hypoglycemic agents, the sulfonylureas such as tolbutamide and the biguanide phenformin, are useful agents for the treatment of the stable maturity-onset diabetes.
This entry has not yet been fully updated (first published 1986; most recently modified version published online November 2010).
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