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单词 sulphaguanidine
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sulphaˈguanidine
sulphaˈguanidine n. [guanidine n.] the poorly absorbed sulphonamide HN:C(NH2)·NH·SO2·C6H4·NH2, formerly used in the treatment of intestinal infections; N1-guanidinylsulphanilamide.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bacteriostatic > sulphonamide > specific
Prontosil1935
Prontosil soluble1936
Albucid1938
Prontosil red1938
sulphapyridine1939
sulphathiazole1939
sulphadiazine1940
succinylsulphathiazole1941
sulphacetamide1941
sulphaguanidine1941
sulphamethazine1942
phthalylsulphathiazole1943
sulfamerazine1943
Sulphamezathine1943
Sulphatriad1948
sulphadimidine1950
sulphamethizole1952
sulphisoxazole1952
sulphamethoxypyridazine1956
sulphamethoxazole1960
sulphafurazole1961
sulphasalazine-
1941 Jrnl. Amer. Med. Assoc. 3 May 2019/2 For 2-sulfanilamidopyrimidine it [sc. the Council on Pharmacy and Chemistry of the American Medical Association] adopted the term sulfadiazine and for sulfanilylguanidine the term sulfaguanidine.
1943 Listener 16 Sept. 321/2 A quite new drug, sulphaguanidine, shows promise for the treatment of bacillary dysentery; it succeeds here..because much of it is not absorbed, and it therefore remains to act in the intestine.
1958 E. Newby Short Walk in Hindu Kush xviii. 220 Everyone..was now suffering from dysentery. We all munched sulphaguanadine tablets but even these failed.
1977 Martindale's Extra Pharmacopoeia (ed. 27) 1483/1 Sulphaguanidine has been employed for the treatment of local intestinal infections..though it has now been largely superseded by the less toxic sulphonamides, phthalylsulphathiazole and succinylsulphathiazole.
extracted from sulpha-sulfa-comb. form
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