substance Pn.

Brit.

/ˌsʌbst(ə)ns ˈpiː/, U.S.

/ˌsəbst(ə)ns ˈpi/

Origin: Formed within English, by compounding. Etymons: substance n., P n.

Etymology: < substance n. + P n.The source of quot. 1931 implies that this was originally an informal laboratory designation, and it is uncertain whether p stood for preparation, powder, precipitate, or something else which is not mentioned in the text.

Physiology.

An undecapeptide found especially in the nervous system and the intestines, which acts on smooth muscle to produce dilation of blood vessels and contraction of the intestines, and is also involved in neurotransmission, esp. in pathways associated with pain.

ΘΚΠ

the world > life > biology > biological processes > action of nervous system > [noun] > reception or transmission of impulses > transmitters

rectifier1895

transmitter1930

sympathin1931

noradrenaline1932

neurohumour1933

substance P1934

norepinephrine1937

neurohormone1939

neurosecretion1956

neurophysin1958

vasoactive intestinal (poly)peptide1958

neurotransmitter1961

VIP1972

neuropeptide1973

1931 U. S. von Euler & J. H. Gaddum in Jrnl. Physiol. 72 80 This standard preparation, which we call P, dissolved easily in water to form a practically clear solution.]

1934 J. H. Gaddum & H. O. Schild in Jrnl. Physiol. 83 1 This unidentified substance has been known in the laboratory for some time as substance P, and will be referred to under this name.

1964 W. G. Smith Allergy & Tissue Metabolism vi. 71 Substance P, which is a pharmacologically active polypeptide.., stimulates guinea pig ileum.

1979 Sci. Amer. July 69/3 Enkephalin and another peptide, substance P, have been implicated in pain perception, substance P with the transmission of pain-related impulses and enkephalin with their suppression.

2004 Chile Pepper June 23/2 The nerves respond to the chemical tickle with a flood of substance P, the chemical that delivers ‘yow’ signals to the brain.

This entry has been updated (OED Third Edition, June 2012; most recently modified version published online March 2022).

单词	substance p
释义	substance Pn. Brit. /ˌsʌbst(ə)ns ˈpiː/, U.S. /ˌsəbst(ə)ns ˈpi/ Origin: Formed within English, by compounding. Etymons: substance n., P n. Etymology: < substance n. + P n.The source of quot. 1931 implies that this was originally an informal laboratory designation, and it is uncertain whether p stood for preparation, powder, precipitate, or something else which is not mentioned in the text. Physiology. An undecapeptide found especially in the nervous system and the intestines, which acts on smooth muscle to produce dilation of blood vessels and contraction of the intestines, and is also involved in neurotransmission, esp. in pathways associated with pain. ΘΚΠ the world > life > biology > biological processes > action of nervous system > [noun] > reception or transmission of impulses > transmitters rectifier1895 transmitter1930 sympathin1931 noradrenaline1932 neurohumour1933 substance P1934 norepinephrine1937 neurohormone1939 neurosecretion1956 neurophysin1958 vasoactive intestinal (poly)peptide1958 neurotransmitter1961 VIP1972 neuropeptide1973 1931 U. S. von Euler & J. H. Gaddum in Jrnl. Physiol. 72 80 This standard preparation, which we call P, dissolved easily in water to form a practically clear solution.] 1934 J. H. Gaddum & H. O. Schild in Jrnl. Physiol. 83 1 This unidentified substance has been known in the laboratory for some time as substance P, and will be referred to under this name. 1964 W. G. Smith Allergy & Tissue Metabolism vi. 71 Substance P, which is a pharmacologically active polypeptide.., stimulates guinea pig ileum. 1979 Sci. Amer. July 69/3 Enkephalin and another peptide, substance P, have been implicated in pain perception, substance P with the transmission of pain-related impulses and enkephalin with their suppression. 2004 Chile Pepper June 23/2 The nerves respond to the chemical tickle with a flood of substance P, the chemical that delivers ‘yow’ signals to the brain. This entry has been updated (OED Third Edition, June 2012; most recently modified version published online March 2022). < n.1934
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