acetazolamiden.
/əˌsiːtəˈzɒləmʌɪd/, /əˌsɛtəˈzɒləmʌɪd/, /əˌsiːtəˈzəʊləmʌɪd/, /əˌsɛtəˈzəʊləmʌɪd/, U.S. /əˌsidəˈzɑləˌmaɪd/, /əˌsidəˈzoʊləˌmaɪd/ Pharmacology.
A drug that inhibits the enzyme carbonic anhydrase, used in the treatment of glaucoma and epilepsy and as a diuretic (now esp. in the prevention of acute mountain sickness).Chemical name: 5-acetamido-1,3,4-thiadiazole-2-sulfonamide, C4H6N4O3S2.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > cleansing or expelling medicines > [noun] > diuretic > specific
Haarlem oil1885
Salyrgan1924
mersalyl1936
acetazolamide1954
chlorothiazide1957
thiazide1959
triamterene1962
ethacrynic acid1963
frusemide1963
the world > health and disease > healing > medicines or physic > medicines for specific purpose > sedatives, antispasmodics, etc. > [noun] > antispasmodic or anticonvulsant > specific substances or preparations
Dilantin1938
phenytoin1942
Artane1948
Mysoline1949
mephenesin1952
troxidone1952
primidone1953
acetazolamide1954
orphenadrine1957
tetrabenazine1958
ethosuximide1960
methsuximide1965
clonazepam1970
valproic1972
valproate1974
1954 T. H. Maren et al. in Bull. Johns Hopkins Hosp. 95 200 Acetazoleamide..is a specific inhibitor of the widely distributed animal enzyme, carbonic anhydrase.
1962 Lancet 28 Apr. 900/2 In such cases [of acute congestive glaucoma] acetazolamide has proved a useful adjunct to intensive miotic therapy.
1997 J. Krakauer Into Thin Air viii. 109 Dr. Mackenzie was on the radio telling somebody at Camp Two, ‘give Ngawang acetazolamide, dexamethasone, and ten milligrams of sublingual nifedipine.’
2002 Wanderlust Feb.–Mar. 69/2 Acetazolamide (Diamox) tablets can be used for both prevention and treatment of mild high-altitude symptoms.
This entry has been updated (OED Third Edition, September 2009; most recently modified version published online December 2021).
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n.1954