streptozotocinn.

/strɛptəʊˈzɒtəsɪn/

Etymology: formed as streptovaricin n. + -zoto-, of unknown origin + -cin (in -mycin suffix).

Pharmacology.

An antibiotic substance obtained from Streptomyces achromogenes that damages insulin-producing cells and is used to induce diabetes in laboratory animals.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used for research

promotor1947

tremorine1956

promoter1960

streptozotocin1960

oxotremorine1961

1960 J. J. Vaura et al. in Antibiotics Ann. 1959–60 234 Streptozotocin is a new antibiotic produced by a streptomycete isolated from the soil.

1972 Jrnl. Pharmaceut. Sci. 61 491/1 Chemically streptozotocin is a N-methyl-N-nitrosourea derivative..of d-glucosamine.

1976 A. Marble et al. in G. S. Avery Drug Treatment xv. 421/1 Streptozotocin, another hyperglycaemic drug, has been similarly used in cases of malignant insulin-secreting tumour.

1980 Nature 3 Jan. 100/1 Proinsulin mRNA was purified from rat B-cell tumours induced with streptozotocin and nicotinamide.

This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).

单词	streptozotocin
释义	streptozotocinn. /strɛptəʊˈzɒtəsɪn/ Etymology: formed as streptovaricin n. + -zoto-, of unknown origin + -cin (in -mycin suffix). Pharmacology. An antibiotic substance obtained from Streptomyces achromogenes that damages insulin-producing cells and is used to induce diabetes in laboratory animals. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > drugs used for research promotor1947 tremorine1956 promoter1960 streptozotocin1960 oxotremorine1961 1960 J. J. Vaura et al. in Antibiotics Ann. 1959–60 234 Streptozotocin is a new antibiotic produced by a streptomycete isolated from the soil. 1972 Jrnl. Pharmaceut. Sci. 61 491/1 Chemically streptozotocin is a N-methyl-N-nitrosourea derivative..of d-glucosamine. 1976 A. Marble et al. in G. S. Avery Drug Treatment xv. 421/1 Streptozotocin, another hyperglycaemic drug, has been similarly used in cases of malignant insulin-secreting tumour. 1980 Nature 3 Jan. 100/1 Proinsulin mRNA was purified from rat B-cell tumours induced with streptozotocin and nicotinamide. This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018). < n.1960
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