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单词 spike protein
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spike protein
spike protein n. Virology (a) (more fully tail spike protein) a protein forming part of the tail of a bacteriophage; (b) (in various human and animal viruses) a glycoprotein projecting from the envelope which binds to a receptor on the host cell and facilitates entry of the viral genome into the host cell.
ΚΠ
1959 C. Lamanna & M. F. Mallette Basic Bacteriol. (ed. 2) xii. 566 Four distinct proteins have been detected: Head protein, proximal tail protein, spike protein, and distal tail protein.
1968 Progress Nucleic Acid Res. & Molecular Biol. 8 132 Analysis of the proteins of this particle reveals that one of the spike proteins..is missing.
1993 B. A. Chrunyk et al. in J. L. Cleland Protein Folding iv. 47 At permissive temperatures..the mutant tail spike proteins both folded and assembled properly in vivo.
2003 Wall St. Jrnl. 12 May b2/6 In their report, they documented mutations in the spike protein, a key surface molecule that allows coronaviruses to invade cells.
2020 S. K. Saxena et al. in S. K. Saxena Coronavirus Dis. 2019 (COVID-19) i. 3 Studies have demonstrated that SARS-CoV-2 spike protein has higher affinity to the ACE2 receptor as compared with SARS.
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