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单词 solapsone
释义

solapsonen.

/səˈlapsəʊn/
Etymology: < sol- (in soluble adj.) + d)apsone, name of a drug of which solapsone is a more soluble derivative ( < di(paminophenyl)sulphone).
Pharmacology.
A white powder given as tablets or by injection of an aqueous solution for the treatment of leprosy; the hydrated tetrasodium salt of di(p-3-phenyl-1, 3-disulphopropylamino)phenylsulphone, C30H28N2O14S5Na4.xH2O.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for leprosy
promin1937
promizole1944
sulphetrone1947
dapsone1952
solapsone1952
thiacetazone1952
1952 Brit. Pharmaceut. Codex Suppl. 66 Solapsone consists mainly of the tetrasodium salt.
1959 R. G. Cochrane Leprosy in Theory & Pract. xvii. 212 The following sulphone drugs are those most commonly employed in the treatment of leprosy: (a) the parent sulphone..Dapsone (B.P.)..(b) Sulphetrone (Solapsone (B.P.)) administered orally or parenterally; [etc.].
1974 R. M. Kirk et al. Surgery ii. 23 Specific treatment [of leprosy] is with dapsone..or solapsone (Sulphetrone) given orally, or by injection,..twice weekly.
1977 Martindale's Extra Pharmacopoeia (ed. 27) 1505/1 In general, the results with solapsone have not been impressive and it has been superseded by more active drugs.
This entry has not yet been fully updated (first published 1986; most recently modified version published online June 2018).
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n.1952
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