单词 | blood–brain barrier |
释义 | > as lemmasblood–brain barrier blood–brain barrier n. [after French barrière hémato-encéphalique (1927 or earlier) or German Bluthirnschranke (1932 or earlier)] Physiology a barrier to the passage of most ionized and very large molecules from the blood into brain tissue, created by the specialized endothelium of cerebral capillaries. ΚΠ 1934 U. Friedemann & A. Elkeles in Lancet 7 Apr. 719/1 Investigators have become aware of the existence of a selective mechanism regulating the exchange of substances between blood and brain. This mechanism has been described as ‘barrière hémato-encéphalique’ or ‘Bluthirnschranke’. We propose to use the English equivalent and therefore shall speak of the blood-brain barrier or B.B.B. 1954 H. W. Florey Lect. Gen. Pathol. xxxvi. 679 The blood-brain barrier is the least easily passed. Penicillin, for example, does not pass in significant amounts from the blood into the cerebrospinal fluid. 2000 Daily Tel. 23 May 22/2 Second-generation antihistamines..do not readily cross the blood-brain barrier and have much less sedative action. < as lemmas |
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