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单词 slow reacting substance
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slow reacting substance
slow reacting substance n. Physiology (now chiefly historical) any of a group of substances that cause slow contraction of smooth muscle; spec. (more fully slow-reacting substance of anaphylaxis) such a substance (now known to be a mixture of leukotrienes) released by mast cells as part of an allergic response.Abbreviated SRS.
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the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun]
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1939 C. H. Kellaway & E. R. Trethewie in Austral. Jrnl. Exper. Biol. 17 227 The perfusate was also tested for the presence of the substance described by Feldberg and Kellaway (1938) which, after a latent interval, causes contraction of the gut followed by slow relaxation and by characteristic after-changes in the excitability of the muscle. This substance we have called S.R.S. (slow reacting substance).
1961 Biochem. Pharmacol. Aug. 168/2 Ethanolamine inhibits the release of SRS-A (slow reacting substance of anaphylaxis).
2005 K. F. Austen in D. J. Chadwick & J. Goode Mast Cells & Basophils 166 I will first review the events that led to the discovery of the mast cell as the source of the activity originally known as slow reacting substance of anaphylaxis (SRS-) and now termed the cysLTs [= cysteinyl leukotrienes].
extracted from slow-reactingadj.
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