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单词 scleromyxœdema
释义

scleromyxœdeman.

/ˌsklɪərəʊmɪksiːˈdiːmə/
Forms: Also scleromyxedema.
Etymology: < German skleromyxödem (H. H. Gottron 1954, in Arch. f. Dermatol. u. Syphilis CXCIX. 71): see sclero- comb. form and myxoedema n.
Pathology.
A disease characterized by the extensive proliferation of fibroblasts and deposition of mucopolysaccharides in the skin, causing distortions of the features and lichenous eruptions.
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the world > health and disease > ill health > a disease > disorders of visible parts > eruptive diseases > [noun] > other eruptive diseases
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1964 Arch. Dermatol. 89 446/1 Lichen myxedematosus, also known as..scleromyxedema, is a well-known clinical entity.
1968 R. J. Cairns in A. Rook et al. Textbk. Dermatol. II. lv. 1621/2 A variant of lichen myxoedematosus is scleromyxoedema..—the Arndt-Gottron syndrome—in which diffuse thickening of the skin underlies the papules... The features may be distorted by the exaggeration of the facial ridges and flexion of the fingers may be limited.
1977 Lancet 4 June 1208/2 Ten years previously this patient has been treated for scleromyxœdema..with melphalan.
This entry has not yet been fully updated (first published 1982; most recently modified version published online December 2020).
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n.1964
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