biotinn.
/ˈbʌɪətɪn/, U.S. /ˈbaɪətn/ Biochemistry.
A vitamin of the B complex which is essential for various metabolic carboxylation reactions and is found esp. in egg yolk, liver, and yeast. Also called vitamin B7, vitamin H.Biotin functions as a carrier of carboxyl groups in various enzymes that bring about carboxylation reactions. It is bicyclic with fused heterocyclic rings and a carboxylic acid side chain. Formula: C10H16N2O3S.
ΚΠ
1935 Bull. Torrey Bot. Club 62 313 Kögl has recently (1935) given evidence that minute amounts of a hormone which he designates as ‘Biotin a’ may accelerate cell division in yeast as much as 1400%.
1936 Chem. Abstr. 30 7624 (heading) The bios problem. Isolation of crystalline biotin from egg yolk.
1960 D. C. Braungart & R. Buddeke Introd. Animal Biol. (ed. 5) xix. 336 A protein found in raw egg white, avidin, will prevent the absorption of biotin.
1987 E. W. Burr Compan. Bird Med. xi. 69/1 Perosis is a condition thought to be caused by..deficiencies of manganese, biotin, choline, and/or other minerals.
2004 G. McKeith You are what you Eat ii. 43/1 Add a biotin supplement to your diet (50mg daily) to prevent yeast organisms from budding full cycle.
Derivatives
ˈbiotinyl n. an acyl radical or group derived from biotin (frequently attributive or as a formative element in names of compounds).
ΚΠ
1951 Jrnl. Amer. Chem. Soc. 73 4142/1 To prepare biotinyl derivatives of amino acids such as glycine and p-aminobenzoic acid.
1963 Biochem. & Biophysical Res. Communications 13 307 Biotinyl adenylate, the intermediate apparently formed by the bacterial and liver biotin-activating enzymes, reacts with CoA to give biotinyl-CoA as a substrate for oxidation of the biotin side chain.
2002 Analytica Chimica Acta 456 210/1 Dendritic surface groups..double-functionalized with biotinyls and ferrocenyls for the biospecific recognition and electron transfer mediation reactions.
This entry has been updated (OED Third Edition, November 2010; most recently modified version published online December 2021).
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n.1935