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单词 runt disease
释义

> as lemmas

runt disease
runt disease n. a syndrome observed in laboratory animals injected as newborns with lymphoid cells from an adult individual, characterized by growth retardation and abnormalities of the liver, spleen, and lymph nodes (later recognized as a form of graft-versus-host disease).
ΚΠ
1957 Jrnl. Cellular & Compar. Physiol. 50 Suppl. i. 135 Billingham and Brent's ‘runt disease’ seems to obey similar laws.
1978 Jrnl. Immunol. 120 1600 (title) Prolongation of allogeneic skin graft rejection and prevention of runt disease by a combination of drugs acting on neuroendocrine functions.
2003 J. H. Antin & N. A. Kernan in R. I. Handin et al. Blood lx. 2133/1 It was later realized that this secondary disease, or runt disease, was actually a graft-versus-host reaction.
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