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单词 bioequivalence
释义

bioequivalencen.

Brit. /ˌbʌɪəʊᵻˈkwɪvələns/, U.S. /ˌbaɪoʊəˈkwɪv(ə)ləns/; see also equivalence n.
Origin: Formed within English, by compounding. Etymons: bio- comb. form, equivalence n.
Etymology: < bio- comb. form + equivalence n. Compare bioequivalency n.
Pharmacology.
Equivalence in respect of biochemical reactions or pharmacological efficacy; the condition of being bioequivalent.
ΚΠ
1967 Z. Vaněk & J. Majer in D. Gottlieb & P. D. Shaw Antibiotics II. 159 The ‘acetate and the propionate units’ are assumed to be incorporated as the coenzyme-A esters. This implies the bioequivalence of acetate and malonate, and also of propionate and methylmalonate.
1973 Amer. Heart Jrnl. 86 715 The systemic testing and voluntary certification programs instituted by the FDA..do not address the problem of bioequivalence.
1989 Telegraph (Alton, Illinois) 24 Aug. a10/1 Some generic-drug makers stand accused of cheating on bioequivalence tests to win FDA approval.
2005 BRW 24 Mar. 41/1 Bioequivalence is usually demonstrated through a blood test on up to 36 people who have taken a generic or branded version of the drug.
This is a new entry (OED Third Edition, November 2010; most recently modified version published online December 2021).
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n.1967
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