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单词 beta-blocking
释义

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beta-blocking
i. beta receptor (Physiology), one of two categories of adrenergic receptor on organs innervated by sympathetic nerves, which when stimulated increases cardiac action and blood flow and relaxes smooth muscle; beta-blocker (Pharmacology), a drug that prevents the stimulation of beta receptors; so beta-blocking adj.
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the world > life > the body > nervous system > substance of nervous system > [noun] > adrenergic receptor > specific
beta receptor1948
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [adjective] > for the heart
cardiacal1620
cardiac1655
cardiotonic1866
beta-blocking1948
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs
khellin1879
procainamide1950
pronethalol1963
propranolol1964
alprenolol1967
verapamil1967
oxprenolol1968
sotalol1968
perhexiline1969
practolol1969
beta-blocker1970
pindolol1971
acebutolol1972
mexiletine1973
atenolol1974
metoprolol1974
labetalol1975
propafenone1975
amrinone1977
1948 R. P. Ahlquist in Amer. Jrnl. Physiol. 153 596 One type of [adrenotropic] receptor is associated with most of the excitatory functions and with at least one of the inhibitory functions (intestine). The other type is associated with most of the inhibitory functions and with one..excitatory function (myocardium)... Because of the opposite effects..the customary signs, E (excitatory) and I (inhibitory) cannot be applied. Therefore, for convenience they have been designated as the alpha adrenotropic receptors and the beta receptors.
1965 J. H. Burn Lect. Notes Pharmacol. (ed. 8) 8 The β-blocking agents are those which prevent adrenaline from causing relaxation in smooth muscle.
1970 Biol. Abstr. 51 96372 Beta blockers exert a powerful physiological effect primarily on the cardiovascular system.
1977 South China Morning Post (Hong Kong) 22 July 16/4 We're hoping that beta blockers will calm performers without taking the edge off their performance.
1983 D. J. Weatherall et al. Oxf. Textbk. Med. II. xiii. 64 Inhibition of the beta receptor in bronchial smooth muscle is likely to produce a significant increase in airways resistance in asthmatic subjects.
1983 D. J. Weatherall et al. Oxf. Textbk. Med. II. xiii. 66/1 Beta-blocking agents may produce depression and other central nervous system side-effects, such as sleep-disturbances, insomnia, and nightmares.
1986 Here's Health Dec. 28/3 With the advent of calcium channel blockers advertising has mentioned side-effects from beta blockers which were never mentioned during their peak of acceptability.
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