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单词 rheumatoid
释义

rheumatoidadj.

Brit. /ˈruːmətɔɪd/, U.S. /ˈruməˌtɔɪd/
Origin: Formed within English, by derivation; modelled on a French lexical item. Etymons: rheumato- comb. form, -oid suffix.
Etymology: < rheumato- comb. form + -oid suffix, after French rhumatoïde (1825). Compare ancient Greek ῥευματώδης like a flux.
Medicine.
Originally: resembling (that of) rheumatism, rheumatic fever, or rheumatic disease; suffering from or affected with any of these diseases. In later use also: spec. of, relating to, or affected with rheumatoid arthritis.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of joints > [adjective] > rheumatism or arthritis
rheumatic?c1425
rheumatical1684
rheumatismatic1695
rheumatismal1820
rheumatoid1845
rheumatoidal1848
screwmatic1893
palindromic1941
1845 Med. Times 12 241/2 A rheumatic element evinced by the signs proper to the rheumatoid diathesis, such as the exacerbation of the pains by the vicissitudes of the weather.
1849 London Med. Gaz. 8 1045/2 The work [of] a French author, named Goss, who had enumerated a very large class of diseases, under the title rheumatoid, as having a common origin.
1871 Practitioner 7 87 The judicious practitioner will regulate the action of the bowels of his rheumatoid patient by proper diet.
1876 R. Bartholow Pract. Treat. Materia Med. ii. 201 The joints become the seat of rheumatoid pain.
1924 Jrnl. Egyptian Archaeol. 10 84 In the Ebers Papyrus it figures in a prescription for some kind of rheumatoid trouble ‘to relax stiffness’.
1950 Sci. News 15 134 The adrenal cortex may play an important role in the pathogenesis of rheumatic and rheumatoid conditions in man.
1973 Nature 14 Dec. 419/1 The pannus of the rheumatoid joint has the ability to produce an active collagenase and invade and degrade cartilage in vitro.

Compounds

rheumatoid arthritis n. a chronic inflammatory disease characterized by a destructive arthritis typically involving many of the smaller joints of the body, and often having more generalized effects on other organs and tissues.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of joints > [noun] > rheumatism or arthritis
arthritis1543
rheum1667
rheumatism1670
rheumatiz1760
rheumatica1796
arthrosia1822
screwmatic1832
rheumatoid arthritis1859
arthritism1868
polyarthritis1868
osteoarthritis1878
panarthritis1890
screw1897
Still's disease1905
rheumatic1918
osteoarthrosis1932
RA1957
1859 A. B. Garrod Treat. Gout xv. 534 Although unwilling to add to the number of names, I cannot help expressing a desire that one might be found for this disease, not implying any necessary relation between it and either gout or rheumatism. Perhaps Rheumatoid Arthritis would answer the object.
1910 Lancet 26 Mar. 860/1 Dr. Jones passed on to consider the clinical features differentiating acute rheumatoid arthritis from the large group of infective arthritides not hitherto connected with any special germ.
1961 R. D. Baker Essent. Pathol. xxi. 573 When rheumatoid arthritis develops in childhood it is frequently designated Still's disease.
2007 Daily Tel. 24 Oct. 8/5 Nice yesterday recommended three new drugs..for the treatment of rheumatoid arthritis in patients with active disease who have tried two other drugs.
rheumatoid factor n. autoantibody directed against immunoglobulin G (gamma globulin), found in the serum of patients with aggressive rheumatoid arthritis; an autoantibody of this type.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > presence of abnormalities > abnormal substances
feverish mattera1398
haemophaein1845
carboxyhaemoglobin1891
sulphaemoglobin1896
reagin1911
paraprotein1949
rheumatoid factor1949
sickle cell haemoglobin1950
Philadelphia chromosome1961
1949 R. M. Pike et al. in Jrnl. Immunol. 63 447 The property of agglutinating sensitized sheep cells to a marked degree appears to be associated almost exclusively with the serum in rheumatoid arthritis. The phenomenon is due to a factor which is present in the serum-globulins... Until this factor is more completely characterized, it may be conveniently termed the ‘rheumatoid factor’.
1980 Sci. Amer. July 42/2 Among the commonest autoantibodies in man are ‘rheumatoid factors’, a group of antibodies directed against gamma globulin.
2000 Independent 26 July i. 5/1 Scientists have found coffee increased a hallmark early indicator, called the ‘rheumatoid factor’.

Derivatives

rheumaˈtoidal adj. now rare
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of joints > [adjective] > rheumatism or arthritis
rheumatic?c1425
rheumatical1684
rheumatismatic1695
rheumatismal1820
rheumatoid1845
rheumatoidal1848
screwmatic1893
palindromic1941
1848 Lancet 18 Nov. 556/1 The present epidemic was peculiarly disposed to be followed by rheumatoidal affections.
1909 R. L. Jones Arthritis Deformans ix. 167 The presence of vasomotor phenomena, neuralgic pains, or muscular cramps in the opposite hand will be in favour of its being rheumatoidal in nature.
1997 Proc. National Acad. Sci. U.S.A. 94 11760/1 IKK-1/2 will be excellent drug targets for treatment of inflammatory diseases, cancer, rheumatoidal arthritis, and a host of other diseases.
rheumaˈtoidally adv. Obsolete rare
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > disorders of joints > [adverb] > of rheumatism or arthritis
rheumatically1807
rheumatoidally1889
1889 Lancet 9 Nov. 947/2 It is of such sufferers that we constantly ask ourselves..is this case going off rheumatoidally?
This entry has been updated (OED Third Edition, June 2010; most recently modified version published online March 2022).
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adj.1845
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