reninn.

Brit.

/ˈriːnɪn/, U.S.

/ˈrinən/

Origin: A borrowing from Latin, combined with an English element. Etymons: Latin rēnēs , -in suffix¹.

Etymology: < classical Latin rēnēs (plural) kidneys (see reins n.) + -in suffix¹. In sense 2 after German Renin (R. Tigerstedt 1897, in Compt. rend. 12me Congrès Internat. de Méd. 1897 (1899) II. ii. 29).

†1. Medicine. A preparation made from animal kidneys, used in organotherapy. Obsolete. rare.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medical preparations of specific origin > biological product > [noun] > specific

lardc1420

sevumc1440

larding1582

protamine1874

renin1894

serum1895

sturine1896

iodothyrin1897

zymin1901

heparin1918

antireticular cytotoxic serum1942

urokinase1952

cryoprecipitate1956

xenoantiserum1973

anti-serum-

1894 G. M. Gould Illustr. Dict. Med. 940/2 Extracts have been prepared from nearly every organ in the animal body;..cerebrin, from the brain,..ossin, from bones, renin, from the kidneys.

2. Physiology. A proteolytic enzyme produced by the juxtaglomerular cells of the kidney, which acts to convert angiotensinogen to angiotensin.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun]

styptica1400

carrier1844

luciferase1888

luciferin1888

urease1892

peroxidase1899

protease1903

renin1903

phenolase1907

proteinase1907

phytase1908

lecithinase1910

uricase1910

phosphatase1912

prunase1912

phenoloxidase1913

oxytocin1927

phosphomonoesterase1932

androgen1936

phosphorylase1939

slow reacting substance1939

phospholipase1945

plasmin1945

bradykinin1949

nitroreductase1953

cytostatic1964

oncogen1967

autoinducer1968

1903 Jrnl. Physiol. 29 258 They [sc. Tigerstedt and Bergman] conclude therefore that a substance, for which they suggest the name ‘renin’, is normally secreted by the kidney into the renal blood, and that this substance causes a vaso-constriction.

1938 Proc. Soc. Exper. Biol. & Med. 39 215 Renin is an enzyme-like substance which is activated by a kinase-like material contained in the protein fraction of plasma and whole blood.

1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin I preparations of slightly different composition have been described, depending on the sources of the renin and the substrate used.

1998 S. Fried Bitter Pills iii. xxi. 349 Companies were blowing millions trying to develop a drug that lowered blood pressure by disabling renin, an enzyme remarkably similar in structure to the HIV protease.

This entry has been updated (OED Third Edition, December 2009; most recently modified version published online March 2022).

单词	renin
释义	reninn. Brit. /ˈriːnɪn/, U.S. /ˈrinən/ Origin: A borrowing from Latin, combined with an English element. Etymons: Latin rēnēs , -in suffix¹. Etymology: < classical Latin rēnēs (plural) kidneys (see reins n.) + -in suffix¹. In sense 2 after German Renin (R. Tigerstedt 1897, in Compt. rend. 12me Congrès Internat. de Méd. 1897 (1899) II. ii. 29). †1. Medicine. A preparation made from animal kidneys, used in organotherapy. Obsolete. rare. ΘΚΠ the world > health and disease > healing > medicines or physic > medical preparations of specific origin > biological product > [noun] > specific lardc1420 sevumc1440 larding1582 protamine1874 renin1894 serum1895 sturine1896 iodothyrin1897 zymin1901 heparin1918 antireticular cytotoxic serum1942 urokinase1952 cryoprecipitate1956 xenoantiserum1973 anti-serum- 1894 G. M. Gould Illustr. Dict. Med. 940/2 Extracts have been prepared from nearly every organ in the animal body;..cerebrin, from the brain,..ossin, from bones, renin, from the kidneys. 2. Physiology. A proteolytic enzyme produced by the juxtaglomerular cells of the kidney, which acts to convert angiotensinogen to angiotensin. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > other stimulators or inhibitors > [noun] styptica1400 carrier1844 luciferase1888 luciferin1888 urease1892 peroxidase1899 protease1903 renin1903 phenolase1907 proteinase1907 phytase1908 lecithinase1910 uricase1910 phosphatase1912 prunase1912 phenoloxidase1913 oxytocin1927 phosphomonoesterase1932 androgen1936 phosphorylase1939 slow reacting substance1939 phospholipase1945 plasmin1945 bradykinin1949 nitroreductase1953 cytostatic1964 oncogen1967 autoinducer1968 1903 Jrnl. Physiol. 29 258 They [sc. Tigerstedt and Bergman] conclude therefore that a substance, for which they suggest the name ‘renin’, is normally secreted by the kidney into the renal blood, and that this substance causes a vaso-constriction. 1938 Proc. Soc. Exper. Biol. & Med. 39 215 Renin is an enzyme-like substance which is activated by a kinase-like material contained in the protein fraction of plasma and whole blood. 1959 A. White et al. Princ. Biochem. (ed. 2) xxx. 750 Hypertensin I preparations of slightly different composition have been described, depending on the sources of the renin and the substrate used. 1998 S. Fried Bitter Pills iii. xxi. 349 Companies were blowing millions trying to develop a drug that lowered blood pressure by disabling renin, an enzyme remarkably similar in structure to the HIV protease. This entry has been updated (OED Third Edition, December 2009; most recently modified version published online March 2022). < n.1894
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