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单词 releasing factor
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releasing factor
releasing factor n. Physiology a peptide released from the hypothalamus into the portal system of the pituitary gland which stimulates the release of a specific hormone from the anterior pituitary.
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releasing factor1962
1955 Endocrinology 57 443 Posterior pituitary extracts contain a corticotropin-releasing factor (CRF) that stimulates the release of ACTH from rat anterior pituitary tissue in vitro.]
1962 Gen. & Compar. Endocrinol. 2 113 The best hypothesis of the general functional mechanism of the eminential component is that the ‘releasing factor’ or ‘releasing factors’ are formed in hypothalamic neurosecretory cells where they become associated with neurosecretory material.
1977 Time 24 Oct. 42/2 Andrew Schally..isolated identified and synthesized three separate hormones—‘releasing factors’—by which the hypothalamus directs the release of key hormones from the pituitary.
2008 Molecular & Cellular Endocrinol. 286 3/1 The isolation and characterization of TRF (TRH) in 1968 made the hypothesis of the existence of hypothalamic releasing factors into a scientific fact.
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