rapamycinn.

Brit.

/ˌrapəˈmʌɪsɪn/, U.S.

/ˌræpəˈmaɪsᵻn/

Origin: From a proper name, combined with an English element. Etymons: proper name Rapa Nui , -mycin suffix.

Etymology: < rapa (in Rapa Nui, local name of Easter Island, where the streptomycete was obtained) + -mycin suffix.

Pharmacology.

A macrolide with antifungal activity produced by the bacterium Streptomyces hygroscopicus, now used chiefly as an immunosuppressant drug.

ΘΚΠ

the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > immuno-suppressant > specific

prednisolone1955

prednisone1955

rapamycin1975

cyclosporin1976

1975 Jrnl. Antibiotics (Tokyo) 28 721 The antifungal principle was extracted with organic solvent from the mycelium, isolated in crystalline form and named rapamycin. Rapamycin is mainly active against Candida albicans.

1993 New Scientist 17 July 18/1 Rapamycin is produced by the microbe Streptomyces hygroscopicus, which is grown from a strain found originally in soil samples on Easter Island.

1999 Times 28 June 9/2 Rapamycin, a drug that suppresses rejection of the transplant, is producing excellent results in trials.

2005 N.Y. Times (National ed.) 31 Mar. a14/1 Doctors found that the immunosuppressive drug sirolimus, or rapamycin, completely reversed the cancer, called Kaposi's sarcoma, in 15 patients.

This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022).

单词	rapamycin
释义	rapamycinn. Brit. /ˌrapəˈmʌɪsɪn/, U.S. /ˌræpəˈmaɪsᵻn/ Origin: From a proper name, combined with an English element. Etymons: proper name Rapa Nui , -mycin suffix. Etymology: < rapa (in Rapa Nui, local name of Easter Island, where the streptomycete was obtained) + -mycin suffix. Pharmacology. A macrolide with antifungal activity produced by the bacterium Streptomyces hygroscopicus, now used chiefly as an immunosuppressant drug. ΘΚΠ the world > health and disease > healing > medicines or physic > medicines for specific purpose > [noun] > immuno-suppressant > specific prednisolone1955 prednisone1955 rapamycin1975 cyclosporin1976 1975 Jrnl. Antibiotics (Tokyo) 28 721 The antifungal principle was extracted with organic solvent from the mycelium, isolated in crystalline form and named rapamycin. Rapamycin is mainly active against Candida albicans. 1993 New Scientist 17 July 18/1 Rapamycin is produced by the microbe Streptomyces hygroscopicus, which is grown from a strain found originally in soil samples on Easter Island. 1999 Times 28 June 9/2 Rapamycin, a drug that suppresses rejection of the transplant, is producing excellent results in trials. 2005 N.Y. Times (National ed.) 31 Mar. a14/1 Doctors found that the immunosuppressive drug sirolimus, or rapamycin, completely reversed the cancer, called Kaposi's sarcoma, in 15 patients. This is a new entry (OED Third Edition, December 2008; most recently modified version published online March 2022). < n.1975
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