/ˈkɪnəliːn/, U.S. /ˈkɪnəlɪn/, 1800s– quinolein, 1800s– quinoleine, 1800s– quinolene, 1800s– quinoline. quinolinen.
/ˈkwɪnəliːn/, /ˈkwɪnl̩iːn/, /ˈkwɪnəlɪn/, /ˈkwɪnl̩ɪn/, U.S. /ˈkwɪnəl(ə)n//ˈkɪnəliːn/, U.S. /ˈkɪnəlɪn/, 1800s– quinolein, 1800s– quinoleine, 1800s– quinolene, 1800s– quinoline. Chemistry.
A pungent, colourless, heterocyclic liquid present in coal tar and used in the manufacture of dyes, in chemical synthesis, and as a solvent.Quinoline has a bicyclic molecule consisting of fused benzene and pyridine rings. Formula: C9H7N.
ΚΠ
1845 W. Gregory Outl. Chem. ii. 481 Quinoline..is formed artificially, by distilling quinine, cinchonine, or strychnine, along with caustic potash.
1882 Manufacturer & Builder June 135/1 A. W. Hoffmann showed that quinoleine was identical with one of the bases which Runge had discovered in coal tar.
1883–4 Med. Ann. 14/1 Chinoline..is a transparent, colourless, mobile oil.
1955 Sci. Amer. July 66/1 Some of the products already evolving are..new pharmaceuticals based on quinoline (nicotinic acid) and on picoline (tuberculosis drugs).
1983 R. O. C. Norman & D. J. Waddington Mod. Org. Chem. (ed. 4) xii. 173 Sulphur and quinoline are added as a poison to prevent the reduction of the aldehyde to the primary alcohol.
2002 J. G. Speight Chem. & Process Design Handbk. 2.442 Quinoline is isolated from coal-tar distillates in a process in which the tar acids are removed by caustic extraction, and the oil is distilled.
This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).
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