quinidinen.

Brit.

/ˈkwɪnᵻdiːn/, U.S.

/ˈkwɪnəˌdin/

Forms: 1800s quinodine, 1800s– quinidin, 1800s– quinidine.

Origin: A borrowing from French. Etymon: French quinidine.

Etymology: < French quinidine (O. Henry and A. Delondre 1833, in Jrnl. de pharmacie 19 624) < quinine quinine n. with apparently arbitrary insertion of -id-.

Chemistry and Pharmacology.

An alkaloid that is the dextrorotatory stereoisomer of quinine, occurring naturally in small quantities in cinchona bark, and used in the treatment of malaria and of cardiac arrhythmia.

ΚΠ

1836 J. M. Gully tr. F. Magendie Formulary (ed. 2) 68 There remains another alkaloid substance, found in 1833, in the yellow cinchona, by MM. Henry and Delondre... This is quinodine.

1856 Proc. Royal Soc. 8 340 Quinidin, which I can now identify as the β-quinine of Von Heijningen, possesses the phenomenon of fluorescence..as powerfully as α-quinine.

1880 C. R. Markham Peruvian Bark 324 Their bark was found to produce the more efficacious alkaloid quinidine, instead of..chinchonine.

1923 Science 4 May 512/1 It was the light waves from the violet end of the spectrum that were the most effective in increasing the toxicity of quinin and quinidin.

1954 Lancet 8 May 957/1 It is now established that procainamide is superior to quinidine in the treatment of ventricular tachycardia.

1979 J. Hodgins Resurrection of Joseph Bourne (1980) iii. iii. 208 He refused to take his quinidine tablets, he refused to eat, he wouldn't talk to his doctor.

2000 Esquire June 74 (advt.) Concomitant use of Paxil with..drugs that inhibit this enzyme (e. g. quinidine) may require lower doses.

This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).

单词	quinidine
释义	quinidinen. Brit. /ˈkwɪnᵻdiːn/, U.S. /ˈkwɪnəˌdin/ Forms: 1800s quinodine, 1800s– quinidin, 1800s– quinidine. Origin: A borrowing from French. Etymon: French quinidine. Etymology: < French quinidine (O. Henry and A. Delondre 1833, in Jrnl. de pharmacie 19 624) < quinine quinine n. with apparently arbitrary insertion of -id-. Chemistry and Pharmacology. An alkaloid that is the dextrorotatory stereoisomer of quinine, occurring naturally in small quantities in cinchona bark, and used in the treatment of malaria and of cardiac arrhythmia. ΚΠ 1836 J. M. Gully tr. F. Magendie Formulary (ed. 2) 68 There remains another alkaloid substance, found in 1833, in the yellow cinchona, by MM. Henry and Delondre... This is quinodine. 1856 Proc. Royal Soc. 8 340 Quinidin, which I can now identify as the β-quinine of Von Heijningen, possesses the phenomenon of fluorescence..as powerfully as α-quinine. 1880 C. R. Markham Peruvian Bark 324 Their bark was found to produce the more efficacious alkaloid quinidine, instead of..chinchonine. 1923 Science 4 May 512/1 It was the light waves from the violet end of the spectrum that were the most effective in increasing the toxicity of quinin and quinidin. 1954 Lancet 8 May 957/1 It is now established that procainamide is superior to quinidine in the treatment of ventricular tachycardia. 1979 J. Hodgins Resurrection of Joseph Bourne (1980) iii. iii. 208 He refused to take his quinidine tablets, he refused to eat, he wouldn't talk to his doctor. 2000 Esquire June 74 (advt.) Concomitant use of Paxil with..drugs that inhibit this enzyme (e. g. quinidine) may require lower doses. This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022). < n.1836
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