pyrimethaminen.
/ˌpɪrᵻˈmɛθəmiːn/, U.S. /ˌpɪrəˈmɛθəˌmin/ Pharmacology.
An antibiotic used in the treatment of malaria, toxoplasmosis, and other protozoal infections.Chemical name: 5-(4-chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, C12H13ClN4.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for malaria
Plasmochin1926
Plasmoquine1926
atebrin1932
quinacrine1934
pamaquin1941
Paludrine1944
chloroquine1946
Resochin1946
proguanil1948
primaquine1949
hydroxychloroquine1951
pyrimethamine1952
mefloquine1974
qinghaosu1979
1952 Indian Jrnl. Malariol. 6 435 (title) Effect of pyrimethamine in human malaria.
1961 New Scientist 20 Apr. 120/1 Pyrimethamine resistance has appeared in some districts in East Africa.
1976 Lancet 4 Dec. 1257/1 When a dose of 25 mg weekly is taken for malarial prophylaxis, pyrimethamine is unlikely to produce adverse hæmatological effects except in those actually or potentially folate deficient.
2001 N. Jones Rough Guide Trav. Health ii. 290 If oral quinine is used, a 7-day course..has to be followed by Fansidar (a combination drug of pyrimethamine and sulfadoxine..) or a 7-day course of doxycycline.
This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).
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n.1952