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单词 pyknosis
释义

pyknosisn.

Brit. /pɪkˈnəʊsɪs/, U.S. /pɪkˈnoʊsəs/
Inflections: Plural pyknoses.
Forms: 1900s– pycnosis, 1900s– pyknosis.
Origin: A borrowing from Greek; modelled on a German lexical item. Etymon: Greek πύκνωσις.
Etymology: < ancient Greek πύκνωσις condensation, condensed matter ( < πυκνοῦν to make dense or solid ( < πυκνός dense, closely packed: see pycno- comb. form) + -ωσις -osis suffix), after German Pyknose (H. Schmaus 1895, in Archiv f. pathol. Anat. u. Physiol. 138 Suppl. 32, as Pycnose ). Compare pyknotic adj.Although the German word is sometimes attributed to W. Pfitzner, it does not appear to be used in his work.
Cell Biology.
Reduction in size and increase in staining of a cell or (more commonly) its nucleus, usually indicating degeneration or necrosis; an instance of this.
ΘΚΠ
the world > life > biology > biological processes > cellular processes > [noun] > degeneration
senescence1879
pyknosis1900
Nissl degeneration1911
1900 W. Myers tr. P. Ehrlich & A. Lazarus Histol. Blood 61 The nuclei of cells which are with certainty to be reckoned among the normoblasts are marked by the absence of structure, their sharply defined contour, their intense affinity for nuclear stains. That is by properties which histology sums up under the name Pyknosis [Ger. Pyknose] (Pfitzner) and recognises as signs of old age.
1926 Arch. Neurol. & Psychiatry (Chicago) 16 135 In general there is a progressive shrinking and pyknosis of the nucleus.
1945 Bot. Rev. 11 148 While some cells showed complete pycnosis, normal telophase stages and cytoses occurred.
1952 Lancet 31 May 1084/2 Sodium salicylate injection produced in the thymus, lymph-nodes, and spleen very numerous nuclear pyknoses of lymphocytes.
1985 W. Frain-Bell Cutaneous Photobiol. vii. 144 Photosensitization then results in cytoplasmic vacuolation, nuclear pyknosis, and a rounding up of the cell body.
2004 Injury 36 695/2 Apoptosis is characterized morphologically by cell shrinking, with cytoplasmatic condensation (apoptotic bodies), nuclear condensation (pycnosis) and DNA-fragmentation.
This entry has been updated (OED Third Edition, December 2007; most recently modified version published online March 2022).
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n.1900
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