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单词 protropin
释义

protropinn.

Brit. /prəʊˈtrəʊpɪn/, U.S. /proʊˈtroʊp(ə)n/
Forms: also with capital initial.
Origin: Formed within English, by derivation. Etymons: pro- prefix2, corticotropin n. at corticotrophic adj. Derivatives, lipotropin n.
Etymology: < pro- prefix2 + -tropin (in corticotropin n. at corticotrophic adj. Derivatives, lipotropin n., etc., hormones of which protropin is a precursor). Compare -tropin comb. form.
Biochemistry and Pharmacology.
A polypeptide growth hormone isolated from the pituitary gland; esp. a genetically engineered form of this for therapeutic use.A proprietary name in the United States.
ΚΠ
1981 A. B. Lerner in Peptides of Pars Intermedia: Ciba Found. Symp. 1980 3 The precursor molecule, here called protropin, is processed by the four types of cell to give rise to different ratios of corticotropin, CLIP, beta- and gamma-lipotropin, alpha-, beta- and gamma-endorphins and alpha-, beta- and gamma-melanotropins.
1985 Science 1 Nov. 523/3 The Genentech product, called Protropin, has the same chemical makeup as the natural hormone except that the synthetic version has an extra methionine group.
1988 Daily Tel. 18 Apr. 13/5 Protropin..may help heal burns when used as a nutritional supplement.
2004 J. C. Avise Hope, Hype, & Reality Genetic Engin. iii. 20 In 1999, the University of California won a $200 million settlement from Genentech for patent infringement related to Protropin, the company's own costly rhGH drug.
This is a new entry (OED Third Edition, September 2007; most recently modified version published online March 2022).
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n.1981
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