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单词 pseudohypoparathyroidism
释义

pseudohypoparathyroidismn.

Brit. /ˌs(j)uːdəʊˌhʌɪpəʊparəˈθʌɪrɔɪdɪz(ə)m/, U.S. /ˈˌsudoʊˌhaɪpoʊˌpɛrəˈθaɪrɔɪˌdɪz(ə)m/
Origin: Formed within English, by compounding. Etymons: pseudo- comb. form, hypoparathyroidism n.
Etymology: < pseudo- comb. form + hypoparathyroidism n.
Medicine.
An inherited disorder in which the biochemical findings of hypoparathyroidism (hypocalcaemia and hyperphosphataemia) occur in the presence of a normal or elevated level of parathyroid hormone, frequently accompanied by skeletal and other abnormalities.The most common form of pseudohypoparathyroidism exhibits autosomal dominant inheritance and is caused by defects in the stimulatory guanine nucleotide-binding protein.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disordered secretion > [noun] > hormonal disorders
hyperthyroidism1900
hypothyroidism1905
hyperpituitarism1909
hypopituitarism1909
hypoparathyroidism1910
thyrotoxicosis1911
hyperparathyroidism1917
hypogonadism1918
Cushing's disease1934
Cushing's syndrome1934
panhypopituitarism1941
pseudohypoparathyroidism1942
Sheehan's syndrome1950
Stein–Leventhal syndrome1950
pseudopseudohypoparathyroidism1952
aldosteronism1954
hyperaldosteronism1955
Albright's dystrophy1957
Albright's hereditary osteodystrophy1962
1942 F. Albright et al. in Endocrinology 30 922 (heading) Pseudo-hypoparathyroidism—an example of ‘Seabright-Bartan Syndrome’.
1966 G. P. Wright & W. S. Symmers Systemic Pathol. II. xxxii. 1126/2 In pseudohypoparathyroidism..the epiphyses and sutures close early, with the result that the patient is short and thickset in stature and has a characteristic round face.
1976 Lancet 20 Nov. 1106/2 Among suggested causes [of neonatal hypocalcaemia] are..decreased responsiveness of end~organs to parathyroid hormone (a form of pseudohypoparathyroidism), and vitamin-D deficiency.
1991 D. J. Weatherall New Genetics & Clin. Pract. (ed. 3) vi. 181 The first disease in which a G protein abnormality was found was a condition called pseudohypoparathyroidism.

Derivatives

ˌpseudoˌhypoparaˈthyroid adj.
ΘΚΠ
the world > health and disease > ill health > a disease > disorders of internal organs > disordered secretion > [adjective] > hormonal disorders
hypothyroid1909
hypoparathyroid1910
hyperthyroid1916
hyperthyroidic1916
hypothyroidic1916
hypopituitary1921
hyperpituitary1924
hypogonadal1933
pseudohypoparathyroid1950
hyperparathyroid1961
1950 Jrnl. Pediatrics 36 567 (title) Pseudohypoparathyroid tetany.
1977 Jrnl. Clin. Endocrinol. & Metabolism 44 420 The resultant changes in renal excretion of adenosine 6':5' monophosphate (cyclic AMP) and inorganic phosphate have been measured in five pseudohypoparathyroid, four hypoparathyroid, and one pseudopseudohypoparathyroid patient.
1992 Biol. Neonate 62 113 Such renal resistance is well known in type 1 pseudohypoparathyroid patients.
This entry has been updated (OED Third Edition, September 2007; most recently modified version published online March 2022).
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n.1942
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更新时间:2024/11/10 23:19:28