propidiumn.

Brit.

/prə(ʊ)ˈpɪdɪəm/, U.S.

/proʊˈpɪdiəm/

Origin: Formed within English, by derivation. Etymons: propyl n., -ide suffix, -ium suffix.

Etymology: < prop- (in propyl n.) + -ide suffix + -ium suffix, after ethidium n.

Biochemistry.

A dye (more fully propidium iodide) which is a salt of a cation related to phenanthridine and is used as a fluorescent stain for DNA, to which it binds by intercalating between the bases.Formula: C₂₇H₃₄N₄I₂.

ΚΠ

1969 B. Hudson et al. in Proc. National Acad. Sci. U.S.A. 62 813 We have found that an ethidium analogue.., which we refer to as propidium iodide (PI), enhances the resolution between closed and open DNA by a factor of 1.8 relative to ethidium bromide.

1981 Jrnl. Histochem. & Cytochem. 29 929 Qualitative and quantitative aspects of the fluorescent propidium diiodide (PI) staining method have been investigated with model films of polyacrylamide gel.

1990 EMBO Jrnl. 9 3885/1 The incorporation of DPA into this peptide could be specifically suppressed by propidium, which suggests that it is part of the peripheral anionic site.

2002 Carcinogenesis 23 2032/1 Pretreated HeLa cells were harvested and suspended in 1 ml of hypotonic fluorochrome solution (50 μg/ml propidium iodide in 0.1% sodium citrate containing 0.1% Triton X-100).

This is a new entry (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	propidium
释义	propidiumn. Brit. /prə(ʊ)ˈpɪdɪəm/, U.S. /proʊˈpɪdiəm/ Origin: Formed within English, by derivation. Etymons: propyl n., -ide suffix, -ium suffix. Etymology: < prop- (in propyl n.) + -ide suffix + -ium suffix, after ethidium n. Biochemistry. A dye (more fully propidium iodide) which is a salt of a cation related to phenanthridine and is used as a fluorescent stain for DNA, to which it binds by intercalating between the bases.Formula: C₂₇H₃₄N₄I₂. ΚΠ 1969 B. Hudson et al. in Proc. National Acad. Sci. U.S.A. 62 813 We have found that an ethidium analogue.., which we refer to as propidium iodide (PI), enhances the resolution between closed and open DNA by a factor of 1.8 relative to ethidium bromide. 1981 Jrnl. Histochem. & Cytochem. 29 929 Qualitative and quantitative aspects of the fluorescent propidium diiodide (PI) staining method have been investigated with model films of polyacrylamide gel. 1990 EMBO Jrnl. 9 3885/1 The incorporation of DPA into this peptide could be specifically suppressed by propidium, which suggests that it is part of the peripheral anionic site. 2002 Carcinogenesis 23 2032/1 Pretreated HeLa cells were harvested and suspended in 1 ml of hypotonic fluorochrome solution (50 μg/ml propidium iodide in 0.1% sodium citrate containing 0.1% Triton X-100). This is a new entry (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1969
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