properdinn.

Brit.

/prəʊˈpəːdɪn/, U.S.

/proʊˈpərd(ə)n/

Origin: A borrowing from Latin, combined with English elements. Etymons: pro- prefix¹, Latin perdere , -in suffix¹.

Etymology: < pro- prefix¹ + perd- (in classical Latin perdere to destroy: see perdition n.) + -in suffix¹.In quot. 1954, coinage of the term is attributed to H. Hirschmann, by personal communication.

Physiology.

Any of a group of proteins found in the blood and involved in the alternative pathway of complement activation.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of

Russell body1892

precipitin1900

nephrotoxin1902

hepatotoxin1903

opsonin1903

autoantibody1905

concanavalin1917

isoantibody1919

reagin1925

immune globulin1934

macroglobulin1952

immunoglobulin1953

properdin1954

LATS1961

alloantibody1964

xenoantibody1974

monoclonal1980

abzyme1986

1954 L. Pillemer et al. in Science 20 Aug. 279/1 This protein, tentatively named properdin.., acts only in conjunction with complement and Mg^{+ +}... Properdin is a normal serum constituent and differs from antibody in many respects, particularly in its lack of specificity and in its exact requirements. [Note] Hans Hirschmann..suggested this name.

1975 Spragg & Gigli in A. Mathieu & B. D. Kahan Immunol. Aspects Anesthetic & Surg. Pract. vi. 116 Properdin has been highly purified as a distinct protein with a molecular weight of 223,000 daltons.

1988 A. M. Silverstein Hist. Immunol. ix. 243 Pillemer described a new substance, properdin , which was held to be a significant contributor to natural (nonantibody) immunity.

2002 Proc. National Acad. Sci. U.S.A. 99 1498/2 Properdin..is a C3-convertase stabilizer that functions in the activation of the alternative complement pathway.

This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).

单词	properdin
释义	properdinn. Brit. /prəʊˈpəːdɪn/, U.S. /proʊˈpərd(ə)n/ Origin: A borrowing from Latin, combined with English elements. Etymons: pro- prefix¹, Latin perdere , -in suffix¹. Etymology: < pro- prefix¹ + perd- (in classical Latin perdere to destroy: see perdition n.) + -in suffix¹.In quot. 1954, coinage of the term is attributed to H. Hirschmann, by personal communication. Physiology. Any of a group of proteins found in the blood and involved in the alternative pathway of complement activation. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of Russell body1892 precipitin1900 nephrotoxin1902 hepatotoxin1903 opsonin1903 autoantibody1905 concanavalin1917 isoantibody1919 reagin1925 immune globulin1934 macroglobulin1952 immunoglobulin1953 properdin1954 LATS1961 alloantibody1964 xenoantibody1974 monoclonal1980 abzyme1986 1954 L. Pillemer et al. in Science 20 Aug. 279/1 This protein, tentatively named properdin.., acts only in conjunction with complement and Mg^{+ +}... Properdin is a normal serum constituent and differs from antibody in many respects, particularly in its lack of specificity and in its exact requirements. [Note] Hans Hirschmann..suggested this name. 1975 Spragg & Gigli in A. Mathieu & B. D. Kahan Immunol. Aspects Anesthetic & Surg. Pract. vi. 116 Properdin has been highly purified as a distinct protein with a molecular weight of 223,000 daltons. 1988 A. M. Silverstein Hist. Immunol. ix. 243 Pillemer described a new substance, properdin , which was held to be a significant contributor to natural (nonantibody) immunity. 2002 Proc. National Acad. Sci. U.S.A. 99 1498/2 Properdin..is a C3-convertase stabilizer that functions in the activation of the alternative complement pathway. This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022). < n.1954
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