proteolysisn.
/ˌprəʊtɪˈɒlᵻsɪs/, U.S. /ˌproʊdiˈɑləsəs/ Biochemistry.† 2. The separation of the proteins from a protein-containing mixture. Obsolete. rare.Apparently only attested in dictionaries or glossaries.
1. The breaking down of proteins or peptides into simpler substances such as amino acids, esp. by the action of enzymes.
ΚΠ
1880 Brit. Med. Jrnl. 17 Apr. 576/1 (heading) Digestive Proteolysis.
1888 Lancet 4 Feb. 234/2 An examination of the contents of the stomach proved that the gastric juice was diminished in quantity, and proteolysis impaired.
1915 Jrnl. Biol. Chem. 23 377 The present work was undertaken in the hope of providing for the measurement of serum protease a quantitative method sufficiently simple,..and specific for proteolysis.
1953 R. W. Fairbrother Text-bk. Bacteriol. (ed. 7) iii. 32 Proteolysis occurring under aerobic conditions tends to be more complete and is termed decay.
1974 V. B. Mountcastle et al. Med. Physiol. (ed. 13) II. xlv. 1040/2 Thrombin is a highly specific hydrolytic enzyme that produces limited proteolysis of fibrinogen, splitting off two small peptides (fibrinopeptides A and B) by hydrolysis of arginyl-glycyl bonds.
1991 Lancet 3 Aug. 287/1 Bradykinin and kallidin (Lys-bradykinin) are the main peptides generated by limited proteolysis from an inactive precursor, kininogen.
ΚΠ
1890 J. S. Billings National Med. Dict. II Proteolysis, the separation of proteids from a mixture.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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