proteolyseproteolyzev.
/ˈprəʊtɪəlʌɪz/, U.S. /ˈproʊdiəˌlaɪz/ Biochemistry.
transitive. To break down (a protein or peptide) into smaller molecules; to subject to proteolysis.
ΚΠ
1902 Daily Chron. 22 Nov. 6/6 These experiments definitely establish the fact..that an enzyme which actively proteolyses the simpler forms of proteid is present in all parts of the plant body.
1950 Proc. Royal Soc. 1949–50 B. 136 38 Liver extract manufactured from ox liver proteolyzed with papain was used for later batches.
1980 Ann. N.Y. Acad. Sci. 344 323 It is proposed that the thalassemic RBC [= red blood cells] contain efficient proteolytic mechanisms up to the end of their maturation, but these prove incapable of proteolysing the excess alpha chains completely.
1993 Biosci., Biotechnol. & Biochem. 57 940 The disulfide-reduced form of ovalbumin was proteolyzed by subtilisin into three major fragments.
Derivatives
ˈproteolysed adj.
ΚΠ
1911 Jrnl. Amer. Chem. Soc. 33 2047 The proteolyzed cod solutions gave the greatest amount of amino nitrogen.
1948 Trans. Royal Soc. Trop. Med. 41 525 Blood transfusion was not available and treatment was begun with proteolysed liver.
1995 Proc. National Acad. Sci. U.S.A. 92 1218/1 A decameric peptide complexed with the intact HLA-Aw68 is seen to bind to the proteolized molecule in the conventional manner.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
<
v.1902