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单词 proteinosis
释义

proteinosisn.

Brit. /ˌprəʊtᵻˈnəʊsɪs/, U.S. /ˌproʊˌtiˈnoʊsəs/
Inflections: Plural proteinoses.
Origin: Formed within English, by derivation; modelled on a German lexical item. Etymons: protein n., -osis suffix.
Etymology: < protein n. + -osis suffix, after German Proteinose (in Lipoidproteinose: E. Uhrbach in J. Jadassohn Handb. der Haut- u. Geschlechtskrankheiten (1932) XII. 336).
Medicine.
The abnormal accumulation or deposition of protein in tissues or cells.
ΘΚΠ
the world > health and disease > ill health > a disease > diseases of tissue > [noun] > excess of other substances
siderosis1883
uratosis1890
haemosiderosis1909
alkalosis1912
proteinosis1937
metabolic alkalosis1948
1937 Arch. Dermatol. & Syphilol. 35 357 A subsequent microscopic examination revealed the tinctorial and cellular features of lipoid proteinosis.
1954 Ann. Internal Med. 41 163 Lipoid proteinosis is a peculiar abnormality of fat deposition characterized by the appearance of white or yellow plaques and nodules in the skin and mucous membranes.
1974 Arch. Dermatol. 110 594/2 Lipid accumulation in lipoid proteinosis lesions is not due to a primary defect in lipid metabolism, but could be due to secondary adherence to glyco~proteins.
1996 Advances in Exper. Med. & Biol. 389 129 (title) The neuronal ceroid lipofuscinoses (Batten disease): a group of lysosomal proteinoses.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1937
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