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单词 propafenone
释义

propafenonen.

Brit. /prəʊˈpafənəʊn/, U.S. /proʊˈpæfəˌnoʊn/
Forms: 1900s– propafenon, 1900s– propafenone.
Origin: A borrowing from German. Etymon: German Propafenon.
Etymology: < German Propafenon (1972 or earlier) < prop- (in Propyl propyl n.) + -a- (in Amino- amino- comb. form) + fen- , respelling of phen- (in pheno- pheno- comb. form) + -on -one suffix.In form propafenon in quot. 1975 after the German form.
Pharmacology.
A drug with anti-arrhythmic and local anaesthetic properties, used in the treatment of cardiac arrhythmia.Chemical name: 1-[2-[2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenyl-1-propanone; C21H27NO3.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs
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1975 Medizinische Klinik 70 95/2 Propafenon..is an new antiarrhythmic agent with ‘quinidine-like’ localanaesthetic [sic] direct membrane and beta adrenergic blocking actions.
1989 Lancet 3 June 1267/2 Such alternative therapies include drugs of the same electrophysiological class such as propafenone.
2004 Cardiovascular Week (Nexis) 23 Aug. 26 Researchers find that the generic form of propafenone is as safe and effective as the innovator drug in patients with atrial fibrillation.
This is a new entry (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1975
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