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单词 pronethalol
释义

pronethaloln.

Brit. /prəʊˈnɛθəlɒl/, U.S. /ˌproʊˈnɛθəˌlɑl/
Forms: 1900s– pronethalol, 1900s– pronetalol Brit. /prəʊˈnɛtəlɒl/, U.S. /ˌproʊˈnɛdəˌlɑl/.
Origin: Formed within English, by compounding. Etymons: propyl n., naphthyl n., ethanol n., -olol comb. form.
Etymology: < pro- (in propyl n.) + n- (in naphthyl n.) + etha- (in ethanol n.) + -olol comb. form.
Pharmacology.
A beta blocker formerly used in the treatment of angina and cardiac dysrhythmias.Chemical name: 2-isopropylamino-1-(2-naphthyl)ethanol; C15H19NO.Pronethalol is no longer used because it has been found to be a potential carcinogen.
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the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs
khellin1879
procainamide1950
pronethalol1963
propranolol1964
alprenolol1967
verapamil1967
oxprenolol1968
sotalol1968
perhexiline1969
practolol1969
beta-blocker1970
pindolol1971
acebutolol1972
mexiletine1973
atenolol1974
metoprolol1974
labetalol1975
propafenone1975
amrinone1977
1963 Brit. Jrnl. Pharmacol. 21 63 The β-blocking agent pronethalol..significantly reduced the combined toxicity of yohimbine and imipramine.
1964 WHO Chron. 18 439 Pronetalol.
1972 Materials & Technol. V. xxi. 810 Beta receptor blocking drugs such as propranolol and pronethalol find their application in the treatment of certain cardiac conditions.
1987 Molecular Pharmacol. 31 101/2 Drugs with higher lipophilicity, such as..propranolol, metipranolol, doberol, and pronethalol, had a severalfold higher perturbation effect at the hydrocarbon membrane core than at the region close to the polar lipid part.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1963
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