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单词 promizole
释义

promizolen.

Brit. /ˈprəʊmᵻzəʊl/, U.S. /ˈproʊməˌzoʊl/
Forms: also with capital initial.
Origin: Formed within English, by compounding. Etymons: promin n., thiazole n. at thio- comb. form 1
Etymology: < promi- (in promin n.) + -zole (in thiazole n. at thio- comb. form 1).
Pharmacology.
An antibiotic structurally related to promin and dapsone, formerly used in the treatment of leprosy and tuberculosis.Chemical name: 5-[(4-aminophenyl)sulphonyl]-2-thiazolamine; C9H9N3O2S2.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for leprosy
promin1937
promizole1944
sulphetrone1947
dapsone1952
solapsone1952
thiacetazone1952
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for tuberculosis
Koch's tuberculin1890
tuberculin1891
tuberculocidin1891
tuberculocide1892
Sanocrysin1924
promizole1944
streptomycin1944
para-aminosalicylic acid1946
pyrazinamide1947
viomycin1950
Marsilid1952
thiacetazone1952
iproniazid1953
isoniazid1953
isonicotinic hydrazide1956
ethionamide1959
strep1959
rifampicin1966
rifampin1968
the world > health and disease > healing > medicines or physic > medicines for specific purpose > substances acting on bacteria > [noun] > bacteriostatic > specific
promin1937
promizole1944
thiacetazone1952
isoniazid1953
isonicotinic hydrazide1956
ethambutol1961
1944 Proc. Staff Meetings Mayo Clinic 19 26 Promizole is the trade name of 4,2′-diaminophenyl-5′-thiazolesulfone.
1948 San Francisco Call-Bull. 12 Apr. 3/6 Diasone and two companion drugs, promin and promizole, have shown promise against both tuberculosis and leprosy.
1964 P. Feeny Fight against Leprosy xvi. 147 There was coming a steady stream of literature about the effects of promin, diasone, sulphetrone and one more weapon that had been added to the arsenal, promizole.
1989 N.Y. Times (Nexis) 12 Sept. b10/3 On the wards, doctors tested drugs like promizole and streptomycin that eventually led to the virtual elimination of the disease [sc. tuberculosis] in children.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online June 2022).
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n.1944
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