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单词 primaquine
释义

primaquinen.

Brit. /ˈprʌɪməkwʌɪn/, /ˈprɪməkwiːn/, U.S. /ˈpraɪməˌkwɪn/
Origin: Formed within English, by compounding. Etymons: prime adj., chloroquine n.
Etymology: < prime adj. + -quine (in chloroquine n., etc.; compare quinoline n.), with insertion of -a- after pentaquine (see quot. 1949).
Pharmacology.
A synthetic drug used in the treatment of malaria, esp. vivax malaria.Chemical name: 8-(4-amino-1-methylbutylamino)-6-methoxyquinoline; C15H21N3O.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations treating or preventing specific ailments > [noun] > for malaria
Plasmochin1926
Plasmoquine1926
atebrin1932
quinacrine1934
pamaquin1941
Paludrine1944
chloroquine1946
Resochin1946
proguanil1948
primaquine1949
hydroxychloroquine1951
pyrimethamine1952
mefloquine1974
qinghaosu1979
1949 Jrnl. Amer. Med. Assoc. 3 Sept. 26/2 The Malaria Study Section, Laboratory of Tropical Disease, National Institutes of Health..suggested the term ‘primaquine’, to distinguish the compound from ‘pentaquine’ and ‘iso~pentaquine’.
1960 Times 11 Nov. 17/1 Primaquine, one of the newer and most efficient drugs for the treatment of malaria.
1974 M. C. Gerald Pharmacol. iv. 77 Of the 15,000 compounds..screened as substitute antimalarials, only two, chloroquine and primaquine, were found to be superior to quinine.
2005 Jrnl. Travel Med. 12 133 Treatment of vivax malaria with primaquine prevents the relapse of infection from residual liver stages of the parasite.
This entry has been updated (OED Third Edition, June 2007; most recently modified version published online March 2022).
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n.1949
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