precipitinn.

Brit.

/prᵻˈsɪpᵻtɪn/, U.S.

/prəˈsɪpᵻdɪn/

Origin: Formed within English, by derivation. Etymons: precipitate n., -in suffix¹.

Etymology: < precipit- (in precipitate n.) + -in suffix¹. Compare French précipitine (1906 or earlier).The word is attributed (in quot. 1931 at main sense and elsewhere) to Rudolf Kraus, but use has not been traced in any language earlier than quot. 1900 at main sense. Compare precipitinogen n.

Immunology.

An antibody that reacts with antigen to form an insoluble precipitate (visible as a sediment in solution or as a line in an agar gel). Also figurative.

ΘΚΠ

the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of

Russell body1892

precipitin1900

nephrotoxin1902

hepatotoxin1903

opsonin1903

autoantibody1905

concanavalin1917

isoantibody1919

reagin1925

immune globulin1934

macroglobulin1952

immunoglobulin1953

properdin1954

LATS1961

alloantibody1964

xenoantibody1974

monoclonal1980

abzyme1986

1900 Lancet 14 July 99/1 Experiments..with the precipitins of egg albumen and sheep's globulin were made, and in this case also one or other of the precipitins disappeared.

1931 Syst. Bacteriol. (Med. Res. Council) 6 xiii. 424 Kraus named the substance present in the bacterial filtrate precipitinogen while the term precipitin was used to denote the hypothetical substance or antibody formed or set free in the animal body in response to injections of an antigen or precipitinogen.

1966 Lancet 24 Dec. 1397/1 Some natives in the Territory of Papua and New Guinea who have chronic lung disease also have in their sera precipitins against a soluble substance in the roofs of their huts.

1971 ‘D. Halliday’ Dolly & Doctor Bird xiii. 192 I don't think any of us felt anything: we carried our own precipitins, for the moment, against fear and danger.

1990 T. G. Wreghitt & P. Morgan-Capner ELISA in Clin. Microbiol. Lab. xviii. 239 Because fungal infections are common in profoundly immuno-compromised hosts, the host's inability to produce antibodies can make the techniques for precipitin detection unreliable.

Compounds

C1.

precipitin technique n.

ΚΠ

1933 Amer. Jrnl. Bot. 20 308 The experiments reported above thus give no indication that as a result of grafting there is an acquired immunity of stock to scion or of scion to stock demonstrable by the ‘precipitin’ technique employed up to the present.

2001 Med. & Vet. Entomol. 15 293 Bloodmeals were identified using the precipitin technique.

precipitin testing n.

ΚΠ

1937 Q. Rev. Biol. 12 32/1 The results of precipitin testing must be confirmed by those of the ‘conglutinin’ reaction performed simultaneously on the same material.

2004 Jrnl. Equine Vet. Sci. 24 510/2 Precipitin testing demonstrated that 17 to 18 horses in Group A did not have antibodies against a diverse variety of allergens tested.

C2.

precipitin reaction n. the reaction of antibody and antigen to form a visible precipitate; an instance of this.

ΚΠ

1906 Proc. Royal Soc. A. 77 p. xxii (title) On the main source of ‘precipitable’ substances and on the rôle of the homologous proteid on precipitin reactions.

2003 Jrnl. Clin. Investigation 58 551 Immunodiffusion experiments..showed no detectable precipitin reaction between the deficient liver extract and the antibody preparation.

precipitin test n. the precipitin reaction; the use of this, esp. to identify a specific antigen or antibody.

ΘΚΠ

the world > matter > chemistry > organic chemistry > biochemical tests > [noun]

precipitin test1903

1903 Jrnl. Hygiene 3 258 (title) The biological or precipitin test for blood.

1952 M. E. Florey Clin. Appl. Antibiotics I. ii. 31 They..found precipitin tests inconclusive and considered in consequence that the urticaria was not the result of an antibody-antigen reaction.

2003 Jrnl. Vector Ecol. 28 74 Of the 1,092 specimens analyzed with the precipitin test, 87.6% reacted to one or more of the eight antisera tested.

This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022).

单词	precipitin
释义	precipitinn. Brit. /prᵻˈsɪpᵻtɪn/, U.S. /prəˈsɪpᵻdɪn/ Origin: Formed within English, by derivation. Etymons: precipitate n., -in suffix¹. Etymology: < precipit- (in precipitate n.) + -in suffix¹. Compare French précipitine (1906 or earlier).The word is attributed (in quot. 1931 at main sense and elsewhere) to Rudolf Kraus, but use has not been traced in any language earlier than quot. 1900 at main sense. Compare precipitinogen n. Immunology. An antibody that reacts with antigen to form an insoluble precipitate (visible as a sediment in solution or as a line in an agar gel). Also figurative. ΘΚΠ the world > life > biology > substance > process stimulators or inhibitors > antibody > [noun] > types of Russell body1892 precipitin1900 nephrotoxin1902 hepatotoxin1903 opsonin1903 autoantibody1905 concanavalin1917 isoantibody1919 reagin1925 immune globulin1934 macroglobulin1952 immunoglobulin1953 properdin1954 LATS1961 alloantibody1964 xenoantibody1974 monoclonal1980 abzyme1986 1900 Lancet 14 July 99/1 Experiments..with the precipitins of egg albumen and sheep's globulin were made, and in this case also one or other of the precipitins disappeared. 1931 Syst. Bacteriol. (Med. Res. Council) 6 xiii. 424 Kraus named the substance present in the bacterial filtrate precipitinogen while the term precipitin was used to denote the hypothetical substance or antibody formed or set free in the animal body in response to injections of an antigen or precipitinogen. 1966 Lancet 24 Dec. 1397/1 Some natives in the Territory of Papua and New Guinea who have chronic lung disease also have in their sera precipitins against a soluble substance in the roofs of their huts. 1971 ‘D. Halliday’ Dolly & Doctor Bird xiii. 192 I don't think any of us felt anything: we carried our own precipitins, for the moment, against fear and danger. 1990 T. G. Wreghitt & P. Morgan-Capner ELISA in Clin. Microbiol. Lab. xviii. 239 Because fungal infections are common in profoundly immuno-compromised hosts, the host's inability to produce antibodies can make the techniques for precipitin detection unreliable. Compounds C1. precipitin technique n. ΚΠ 1933 Amer. Jrnl. Bot. 20 308 The experiments reported above thus give no indication that as a result of grafting there is an acquired immunity of stock to scion or of scion to stock demonstrable by the ‘precipitin’ technique employed up to the present. 2001 Med. & Vet. Entomol. 15 293 Bloodmeals were identified using the precipitin technique. precipitin testing n. ΚΠ 1937 Q. Rev. Biol. 12 32/1 The results of precipitin testing must be confirmed by those of the ‘conglutinin’ reaction performed simultaneously on the same material. 2004 Jrnl. Equine Vet. Sci. 24 510/2 Precipitin testing demonstrated that 17 to 18 horses in Group A did not have antibodies against a diverse variety of allergens tested. C2. precipitin reaction n. the reaction of antibody and antigen to form a visible precipitate; an instance of this. ΚΠ 1906 Proc. Royal Soc. A. 77 p. xxii (title) On the main source of ‘precipitable’ substances and on the rôle of the homologous proteid on precipitin reactions. 2003 Jrnl. Clin. Investigation 58 551 Immunodiffusion experiments..showed no detectable precipitin reaction between the deficient liver extract and the antibody preparation. precipitin test n. the precipitin reaction; the use of this, esp. to identify a specific antigen or antibody. ΘΚΠ the world > matter > chemistry > organic chemistry > biochemical tests > [noun] precipitin test1903 1903 Jrnl. Hygiene 3 258 (title) The biological or precipitin test for blood. 1952 M. E. Florey Clin. Appl. Antibiotics I. ii. 31 They..found precipitin tests inconclusive and considered in consequence that the urticaria was not the result of an antibody-antigen reaction. 2003 Jrnl. Vector Ecol. 28 74 Of the 1,092 specimens analyzed with the precipitin test, 87.6% reacted to one or more of the eight antisera tested. This entry has been updated (OED Third Edition, March 2007; most recently modified version published online March 2022). < n.1900
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