单词 | postmitotic |
释义 | postmitoticadj.n. Cell Biology. A. adj. Occurring subsequent to mitosis; spec. (of a cell) having ceased (reversibly or irreversibly) to display cell division. ΘΚΠ the world > life > biology > biological processes > genetic activity > [adjective] > mitosis merismatic1849 indirect1880 karyokinetic1885 karyomitoic1885 mitotic1888 mitosic1890 kinetic1894 polymitotic1931 intermitotic1942 postmitotic1942 1942 E. V. Cowdry Probl. Ageing (ed. 2) xxiv. 631 The length of life of the majority of postmitotic nerve cells can be taken to be that of the body less one year. 1962 Lancet 27 Jan. 211/1 The granulocytes are post-mitotic and can be ruled out, and so we are restricted to the ‘mononuclears’. 1968 H. Harris Nucleus & Cytoplasm v. 92 When all the nuclei in the heterokaryon enter mitosis together, post-mitotic reconstitution may produce a single large nucleus at one step. 1971 J. Z. Young Introd. Study Man xxii. 288 Errors in the hereditary instructions and their transcription may be of especial importance in post-mitotic cells. 1987 R. P. Saneto & J. de Vellis in A. J. Turner & H. S. Bachelard Neurochem. ii. 30 Generally, in any CNS area, neurones become post-mitotic before glial cell proliferation takes place. 1993 Cell 74 597/2 The surviving neurons develop into postmitotic cells with extended life spans. B. n. A cell which is unlikely or unable to divide again. ΚΠ 1942 E. V. Cowdry Probl. Ageing (ed. 2) xxiv. 628 The highly specialized cells, formed from the last differentiating intermitotics at the end of the series,..are ‘end cells’. Their individual lives begin..after the last mitosis... In a word, they are postmitotics. 1959 Q. Rev. Biol. 34 135/2 If radiation produces an acceleration of the aging process, we should expect the long-term effects to be mainly in the fixed postmitotics. 1967 P. Alexander in Symp. Soc. Exper. Biol. 21 in Q. Rev. Biol. 56 (1981) 284 When during mammalian development, cells differentiated to be post-mitotics (e.g., nerve or muscle cells) this may be associated with loss of the DNA repair system because this is not immediately needed. This entry has been updated (OED Third Edition, December 2006; most recently modified version published online March 2022). < adj.n.1942 |
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