单词 | porphyria |
释义 | porphyrian. Medicine. Any of a group of inherited or acquired disorders of haem metabolism leading to the increased excretion of porphyrins and associated with a variety of symptoms referable esp. to the skin (chiefly as photosensitivity) and the nervous system. Frequently with distinguishing English or scientific Latin word or words. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > metabolic disorders > [noun] > porphyria haematoporphyria1922 porphyria1923 porphyrism1923 porphyrinopathy1950 1923 A. E. Garrod Inborn Errors Metabolism (ed. 2) viii. 144 Pigmentation of the enamel is a rare phenomenon... Even in congenital porphyria it is evidently an exceptional sign. 1945 Jrnl. Biol. Chem. 157 330 A complex mixture of pigments occurs in porphyria urine. 1961 Lancet 22 July 176/2 Recently, several thousand cases of human porphyria have been seen in Turkey after the consumption of wheat containing 0·1–0·2% of hexachlorobenzene. 1968 New Eng. Jrnl. Med. 18 Apr. 916/2 Patients with porphyria variegata have an increased amount of fecal protoporphyrin and coproporphyrin, a finding not found in those with acute intermittent porphyria. 1987 S. Weintraub Victoria (1988) iii. 65 Suffering from porphyria, the same malady that had enfeebled his father, he was losing his sight. 2002 G. M. Eberhart Mysterious Creatures II. 585/1 Porphyria involves a failure of the bone marrow to form properly. Its symptoms include an aversion to sunlight, tissue destruction of the face and fingers, skin lesions, and a reddish-brown pigmentation on the teeth. This entry has been updated (OED Third Edition, December 2006; most recently modified version published online March 2022). < n.1923 |
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