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单词 polymerase
释义

polymerasen.

Brit. /ˈpɒlᵻməreɪz/, /pəˈlɪməreɪz/, /pɒˈlɪməreɪz/, U.S. /pəˈlɪməˌreɪz/, /pəˈlɪməˌreɪs/
Origin: Formed within English, by derivation. Etymons: polymer n., -ase suffix.
Etymology: < polymer n. + -ase suffix.
Biochemistry.
An enzyme which catalyses the formation of a polymer, esp. a polynucleotide.DNA, RNA polymerase: see the first element.
ΘΚΠ
the world > life > biology > biological processes > genetic activity > genetic components > [noun] > nucleic acid > enzymes
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nucleosidase1911
nucleotidase1911
adenosine deaminase1913
cellobiase1919
hydratase1922
activase1928
hexokinase1930
histaminase1930
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chymotrypsin1933
glycosidase1933
rhodanese1933
acetylcholinesterase1937
prolidase1937
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hydrase1943
isomerase1943
lactoperoxidase1943
streptokinase1944
pectinesterase1945
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phosphokinase1946
alliinase1947
CoA1947
phosphotransferase1948
polymerase1948
transferase1948
elastase1949
amyloglucosidase1950
transacetylase1950
transhydrogenase1952
hydroxylase1953
kinase1953
transketolase1953
synthase1954
hexosaminidase1955
translocase1957
angiotensinase1958
angiotensin converting enzyme1960
photoenzyme1960
acetyltransferase1961
adenyl cyclase1961
adenylate cyclase1962
replicase1962
ADA1963
transcriptase1963
adenylyl cyclase1964
recombinase1964
laminarinase1966
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acrosin1970
reverse transcriptase1970
cellobiohydrolase1972
cyclooxygenase1974
laminaranase1974
primase1977
helicase1978
monodeiodinase1978
transposase1979
maturase1980
1948 Science 9 Apr. 377/1 Attempts were made to increase the yield of desoxyribonucleic acid by adding citrate or phosphate ions to the glycine solution in order to bind magnesium ions, which presumably activate nucleases or polymerases.
1958 Jrnl. Biol. Chem. 233 163/2 The enzyme responsible for deoxyribonucleotide incorporation is designated as ‘polymerase’.
1964 New Scientist 23 Jan. 211/1 DNA has been bio-synthesised from its four basic building blocks put together with the enzyme polymerase and some natural DNA to act as a template.
1973 B. J. Williams Evol. & Human Origins vi. 89/1 RNA polymerase is active when the cell is carrying on its normal metabolic functions.
1994 J. Cohen & I. Stewart Collapse of Chaos iii. 81 There are special sequences on the RNA, called ribozymes, which act like enzymes to cut and paste the RNA sequences that the polymerases copy from the DNA.
2004 Photosynthesis Res. 81 105 Plants also possess..bypass polymerases that enable the plant to replicate its DNA in the absence of DNA repair.

Compounds

polymerase chain reaction n. Molecular Biology a technique for producing many copies of a chosen sequence of genomic DNA using repeated cycles of denaturation, annealing with primer, and replication with DNA polymerase; abbreviated PCR.
ΚΠ
1985 R. K. Saiki et al. in Science 20 Dec. 1350/3 The β-globin segment was amplified by the polymerase chain reaction (PCR) procedure of Mullis and Faloona.
1996 P. H. Duesberg Inventing AIDS Virus vi. 180 The very ability of retroviruses to survive as dormant genes by attaching themselves to human chromosomes has been exploited for the most sensitive HIV assay yet—the Polymerase Chain Reaction.
2000 New Scientist 11 Nov. 89/1 (advt.) Applications are invited for a Technician to work on a project to detect micrometastases in primary breast cancer patients using a combination of immunocytochemistry and quantitative polymerase chain reaction.
This entry has been updated (OED Third Edition, September 2006; most recently modified version published online March 2022).
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n.1948
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