单词 | polycythaemia |
释义 | polycythaemiapolycythemian. Medicine. An abnormally high number or concentration of circulating red blood cells; an instance of this. Also: any disorder characterized by this; esp. (in full polycythaemia rubra, polycythaemia rubra vera, polycythaemia vera), a myeloproliferative disorder in which there is abnormal proliferation of red blood cell precursors, often accompanied by increased numbers of leucocytes and platelets.In absolute polycythaemia there is an increase in circulating red blood cell mass; this may be primary, as in polycythaemia vera, or secondary (to hypoxia or to increased erythropoietin production). Relative polycythaemia results from reduced plasma volume. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [noun] > excess of red corpuscles anhydraemia1851 polycythaemia1857 erythraemia1908 Osler's disease1908 haemoconcentration1940 1857 R. Dunglison Med. Lexicon (rev. ed.) 741/2 Polycythæmia, a condition of the blood in which there is an increase of the red corpuscles. 1881 A. Flint Treat. Princ. Med. (ed. 5) 60 An increase..in the number of the red blood-corpuscles beyond the healthy limit..constitutes..polycythaemia. 1908 Practitioner Feb. 238 It would almost seem better to bring the nomenclature of this new disease into line with that adopted to describe an increase of the various forms of leucocytes, and to call it polycythæmia rubra, erythrocytosis, or, better still, erythrocythæmia. 1947 Nucleonics Dec. 91/2 Among the diseases reported on are polycythemia rubra vera, lymphatic, myelogenous and monocytic leucemias, Hodgkin's Syndrome, metastatic carcinoma and sarcoma and multiple myeloma. 1980 Lancet 19 Jan. 127/2 Blood cells in polycythaemia vera and idiopathic myelofibrosis, like those in chronic granulocytic leukaemia, are derived from a single clone of cells. 1993 S. J. Ettinger Pocket Compan. Textbk. Vet. Internal Med. xxii. 63 Secondary polycythemias are associated with elevated plasma erythropoietin levels. Derivatives ˌpolycyˈthaemic adj. of, involving, or suffering from polycythaemia. ΘΚΠ the world > health and disease > ill health > a disease > disorders of internal organs > disorders of blood > [adjective] > excess of red corpuscles polycythaemic1906 anhydraemic1920 erythraemic1938 1906 Lancet 7 July 20/2 The following case is published as a contribution to the study of the polycythæmic condition. 1935 B. Harrow & C. P. Sherwin Textbk. Biochem. xv. 413 Polycythemic hypovolemia occurs in conditions of..water deprivation. 2001 Proc. National Acad. Sci. U.S.A. 98 986/1 Mice that were homozygous for the mutant human allele were severely polycythemic but viable. This entry has been updated (OED Third Edition, September 2006; most recently modified version published online March 2022). < n.1857 |
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