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单词 practolol
释义

practololn.

Brit. /ˈpraktəlɒl/, U.S. /ˈpræktəˌlɑl/
Origin: Formed within English, by compounding. Etymons: propanol n., propio- comb. form, aceto- comb. form, -olol comb. form.
Etymology: < pr- (in propanol n. , propio- comb. form) + ac- (in aceto- comb. form) + -olol comb. form, with insertion of -t- for euphony.
Pharmacology.
A beta blocker formerly used to treat hypertension and cardiac arrhythmias but withdrawn owing to adverse side effects.Chemical name: 1-(4-acetamidophenoxy)-3-isopropylamino-2-propanol; C14H22N2O3.
ΘΚΠ
the world > health and disease > healing > medicines or physic > medicines for specific purpose > preparations for treating specific parts > [noun] > for the heart > specific drugs
khellin1879
procainamide1950
pronethalol1963
propranolol1964
alprenolol1967
verapamil1967
oxprenolol1968
sotalol1968
perhexiline1969
practolol1969
beta-blocker1970
pindolol1971
acebutolol1972
mexiletine1973
atenolol1974
metoprolol1974
labetalol1975
propafenone1975
amrinone1977
1969 Lancet 14 June 1221/1 The British Pharmacopœia has issued the following supplementary list of approved names... Practolol.
1969 Lancet 2 Aug. 227/1 Practolol..was given to forty-seven patients who had cardiac dysrhythmias after myocardial infarction.
1976 Nature 12 Aug. 595/2 Practolol (40 mg kg−1) a β2 receptor blocking agent that does not enter the brain in significant quantity did not inhibit hyperactivity.
1976 Lancet 6 Nov. 984/1 Practolol (‘Eraldin’) tablets were withdrawn from general use on Oct. 1, 1975.
1993 Daily Tel. 20 July 15/3 That was one of the lessons learnt following the deaths, blindness, dry eyes and skin rashes which followed the mass use of an ICI drug called practolol in the mid-1970s.
This entry has been updated (OED Third Edition, December 2006; most recently modified version published online March 2022).
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n.1969
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