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单词 polyadenylate
释义

polyadenylaten.

Brit. /ˌpɒlɪəˈdɛnᵻleɪt/, U.S. /ˈˌpɑliəˈdɛnəˌleɪt/
Origin: Formed within English, by compounding. Etymons: poly- comb. form, adenylate n.
Etymology: < poly- comb. form + adenylate n. Compare slightly earlier polyadenylic adj. at poly- comb. form 2.
Biochemistry.
A salt or ester, or the anion, of polyadenylic acid; the acid itself.
ΚΠ
1962 Proc. National Acad. Sci. U.S.A. 48 90 This implies that the minimum chain length of the polyadenylate is in the order of 60 to 70 nucleotide residues.
1965 Jrnl. Physical Chem. 69 4372 This band is formed upon reaction with such diverse polymers as polyadenylate, polyaspartate..and denatured DNA.
2002 Crit. Rev. Lab. Sci. 39 193 Polyadenylate polymerase (PAP) is one of the enzymes involved in the formation of the polyadenylate tail of the 3′ end of mRNA.
This is a new entry (OED Third Edition, September 2006; most recently modified version published online March 2022).

polyadenylatev.

Brit. /ˌpɒlɪəˈdɛnᵻleɪt/, U.S. /ˈˌpɑliəˈdɛnəˌleɪt/
Origin: Formed within English, by conversion. Etymon: polyadenylate n.
Etymology: < polyadenylate n.
Biochemistry.
transitive. To attach a polyadenylate moiety to (a nucleotide, nucleic acid, etc.).
ΚΠ
1973 Q. Rev. Biol. 48 596 Other mRNA sequences located there could be successfully polyadenylated and excised.
1988 Science 1 Aug. 1270/1 A second activity in the extract polyadenylates the product under appropriate conditions.

Derivatives

polyaˈdenylated adj.
ΚΠ
1974 Proc. National Acad. Sci. U.S.A. 71 1785/1 Polyadenylated messenger RNA extracted from HeLa cells was hybridized with a mass excess of HeLa DNA.
2003 D. P. Snustad & M. J. Simmons Princ. Genetics (ed. 3) xviii. 452 A structure reminiscent of polyadenylated RNA.
This is a new entry (OED Third Edition, September 2006; most recently modified version published online March 2022).
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n.1962v.1973
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